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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T80526
|
| Target Name |
CSNK2A2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1459
|
| Gene ID |
100063080 (Equus caballus), 101093065 (Felis catus), 13000 (Mus musculus), 1459 (Homo sapiens) 282420 (Bos taurus), 307641 (Rattus norvegicus), 478108 (Canis lupus familiaris), 712455 (Macaca mulatta)
|
| Target Alternative Names |
1110035J23Rik,CK II alpha',CK2,CK2A2,CK2alpha',CSNK2A1,CSNK2A2,Casein kinase II subunit alpha',Csnk2a2
|
| Uniprot Accession |
O54833,P19784,P20427
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
NF-kappa B signaling pathway, Wnt signaling pathway, Adherens junction, Alzheimer disease, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer
|
| Gene Ensembl |
ENSECAG00000014130, ENSMUSG00000046707, ENSG00000070770, ENSBTAG00000013784, ENSCAFG00845002309, ENSMMUG00000015892
|
| Target Classification |
Kinase
|
Pre-made viral vector of CSNK2A2 cDNA Clones/ORF Plasmid
CSNK2A2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1459 | Pre-made Human CSNK2A2/CK2A2/CSNK2A1 siRNA oligo Duplex | 1459 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo307641 | Pre-made Rat Csnk2a2 siRNA oligo Duplex | 307641 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13000 | Pre-made Mouse Csnk2a2/CK2/1110035J23Rik siRNA oligo Duplex | 13000 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712455 | Pre-made Cynomolgus/Rhesus macaque CSNK2A2 siRNA oligo Duplex | 712455 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093065 | Pre-made Cat/Feline CSNK2A2 siRNA oligo Duplex | 101093065 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478108 | Pre-made Dog/Canine CSNK2A2 siRNA oligo Duplex | 478108 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282420 | Pre-made Bovines/Cattle CSNK2A2 siRNA oligo Duplex | 282420 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063080 | Pre-made Equine/Horse CSNK2A2 siRNA oligo Duplex | 100063080 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CSNK2A2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T80526-Ab | Human | Anti-Human CSNK2A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T80526-Ab | Rat | Anti-Rat CSNK2A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T80526-Ab | Mouse | Anti-Mouse CSNK2A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T80526-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CSNK2A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T80526-Ab | Cat/Feline | Anti-Cat/Feline CSNK2A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T80526-Ab | Dog/Canine | Anti-Dog/Canine CSNK2A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T80526-Ab | Bovines/Cattle | Anti-Bovines/Cattle CSNK2A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T80526-Ab | Equine/Horse | Anti-Equine/Horse CSNK2A2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CSNK2A2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T80526-Ag | Human | Human CSNK2A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T80526-Ag | Rat | Rat CSNK2A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T80526-Ag | Mouse | Mouse CSNK2A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T80526-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CSNK2A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T80526-Ag | Cat/Feline | Cat/Feline CSNK2A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T80526-Ag | Dog/Canine | Dog/Canine CSNK2A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T80526-Ag | Bovines/Cattle | Bovines/Cattle CSNK2A2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T80526-Ag | Equine/Horse | Equine/Horse CSNK2A2 recombinant protein | Mammalian cell | Detail |