Explore KCNJ5 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T78692
|
| Target Name |
KCNJ5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3762
|
| Gene ID |
100064621 (Equus caballus), 101091726 (Felis catus), 16521 (Mus musculus), 29713 (Rattus norvegicus)
3762 (Homo sapiens), 489284 (Canis lupus familiaris), 539844 (Bos taurus), 714799 (Macaca mulatta)
|
| Target Alternative Names |
CIR,Cardiac inward rectifier (CIR),G protein-activated inward rectifier potassium channel 4,GIRK-4,GIRK4,Heart KATP channel,Inward rectifier K(+) channel Kir3.4 (IRK-4),KATP-1,KATP1,KCNJ5,KIR3.4,Kcnj5,Kir3.4,LQT13,Potassium channel,inwardly rectifying subfamily J member 5
|
| Uniprot Accession |
P48545,P48548,P48544,F1MYR9
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Circadian entrainment, Serotonergic synapse, Oxytocin signaling pathway, Aldosterone synthesis and secretion, GnRH secretion, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000025007, ENSMUSG00000032034, ENSG00000120457, ENSBTAG00000006902
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of KCNJ5 cDNA Clones/ORF Plasmid
KCNJ5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3762 | Pre-made Human KCNJ5/CIR/GIRK4 siRNA oligo Duplex | 3762 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29713 | Pre-made Rat Kcnj5 siRNA oligo Duplex | 29713 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16521 | Pre-made Mouse Kcnj5/CIR/GIRK4 siRNA oligo Duplex | 16521 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714799 | Pre-made Cynomolgus/Rhesus macaque KCNJ5 siRNA oligo Duplex | 714799 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091726 | Pre-made Cat/Feline KCNJ5 siRNA oligo Duplex | 101091726 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489284 | Pre-made Dog/Canine KCNJ5 siRNA oligo Duplex | 489284 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539844 | Pre-made Bovines/Cattle KCNJ5/GIRK-4/KATP-1 siRNA oligo Duplex | 539844 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064621 | Pre-made Equine/Horse KCNJ5 siRNA oligo Duplex | 100064621 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNJ5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T78692-Ab | Human | Anti-Human KCNJ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T78692-Ab | Rat | Anti-Rat KCNJ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T78692-Ab | Mouse | Anti-Mouse KCNJ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T78692-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNJ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T78692-Ab | Cat/Feline | Anti-Cat/Feline KCNJ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T78692-Ab | Dog/Canine | Anti-Dog/Canine KCNJ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T78692-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNJ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T78692-Ab | Equine/Horse | Anti-Equine/Horse KCNJ5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KCNJ5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T78692-Ag | Human | Human KCNJ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T78692-Ag | Rat | Rat KCNJ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T78692-Ag | Mouse | Mouse KCNJ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T78692-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNJ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T78692-Ag | Cat/Feline | Cat/Feline KCNJ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T78692-Ag | Dog/Canine | Dog/Canine KCNJ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T78692-Ag | Bovines/Cattle | Bovines/Cattle KCNJ5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T78692-Ag | Equine/Horse | Equine/Horse KCNJ5 VLP (virus-like particle) | HEK293 | Products Developing |
