Human KCNJ5/CIR/GIRK4 ORF/cDNA clone-Lentivirus plasmid (NM_000890)

Cat. No.: pGMLP003673
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human KCNJ5/CIR/GIRK4 Lentiviral expression plasmid for KCNJ5 lentivirus packaging, KCNJ5 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP003673
Gene Name KCNJ5
Accession Number NM_000890
Gene ID 3762
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1260 bp
Gene Alias CIR,GIRK4,KATP1,KIR3.4,LQT13
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCTGGCGATTCTAGGAATGCCATGAACCAGGACATGGAGATTGGAGTCACTCCCTGGGACCCCAAGAAGATTCCAAAACAGGCCCGCGATTATGTCCCCATTGCCACAGACCGTACGCGCCTGCTGGCCGAGGGCAAGAAGCCACGCCAGCGCTACATGGAGAAGAGTGGCAAGTGCAACGTGCACCACGGCAACGTCCAGGAGACCTACCGGTACCTGAGTGACCTCTTCACCACCCTGGTGGACCTCAAGTGGCGCTTCAACTTGCTCGTCTTCACCATGGTTTACACTGTCACCTGGCTGTTCTTCGGCTTCATTTGGTGGCTCATTGCTTATATCCGGGGTGACCTGGACCATGTTGGCGACCAAGAGTGGATTCCTTGTGTTGAAAACCTCAGTGGCTTCGTGTCCGCTTTCCTGTTCTCCATTGAGACCGAAACAACCATTGGGTATGGCTTCCGAGTCATCACAGAGAAGTGTCCAGAGGGGATTATACTCCTCTTGGTCCAGGCCATCCTGGGCTCCATCGTCAATGCCTTCATGGTGGGGTGCATGTTTGTCAAGATCAGCCAGCCCAAGAAGAGAGCGGAGACCCTCATGTTTTCCAACAACGCAGTCATCTCCATGCGGGACGAGAAGCTGTGCCTCATGTTCCGGGTGGGCGACCTCCGCAACTCCCACATCGTGGAGGCCTCCATCCGGGCCAAGCTCATCAAGTCCCGGCAGACCAAAGAGGGGGAGTTCATCCCCCTGAACCAGACAGACATCAACGTGGGCTTTGACACGGGCGACGACCGCCTCTTCCTTGTGTCTCCTCTGATCATCTCCCATGAGATCAACCAGAAGAGCCCTTTCTGGGAGATGTCTCAGGCTCAGCTGCATCAGGAAGAGTTTGAAGTTGTGGTCATTCTAGAAGGGATGGTGGAAGCCACAGGCATGACCTGCCAAGCCCGGAGCTCCTACATGGATACAGAGGTGCTCTGGGGCCACCGATTCACACCAGTCCTCACCTTGGAAAAGGGCTTCTATGAGGTGGACTACAACACCTTCCATGATACCTATGAGACCAACACACCCAGCTGCTGTGCCAAGGAGCTGGCAGAAATGAAGAGGGAAGGCCGGCTCCTCCAGTACCTCCCCAGCCCCCCACTGCTGGGGGGCTGTGCTGAGGCAGGGCTGGATGCAGAGGCTGAGCAGAATGAAGAAGATGAGCCCAAGGGGCTGGGTGGGTCCAGGGAGGCCAGGGGCTCGGTGTGA
ORF Protein Sequence MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T78692-Ab Anti-KCNJ5/ CIR/ GIRK4 monoclonal antibody
    Target Antigen GM-Tg-g-T78692-Ag KCNJ5 VLP (virus-like particle)
    ORF Viral Vector pGMLP003673 Human KCNJ5 Lentivirus plasmid
    ORF Viral Vector pGMLV000824 Human KCNJ5 Lentivirus plasmid
    ORF Viral Vector vGMLP003673 Human KCNJ5 Lentivirus particle
    ORF Viral Vector vGMLV000824 Human KCNJ5 Lentivirus particle


    Target information

    Target ID GM-T78692
    Target Name KCNJ5
    Gene Group Identifier
    （Target Gene ID in Homo species)         		3762
    Gene ID 100064621 (Equus caballus), 101091726 (Felis catus), 16521 (Mus musculus), 29713 (Rattus norvegicus)
    3762 (Homo sapiens), 489284 (Canis lupus familiaris), 539844 (Bos taurus), 714799 (Macaca mulatta)
    Gene Symbols & Synonyms KCNJ5,Kcnj5,CIR,GIRK4,KATP-1,Kir3.4,KATP1,LQT13,KIR3.4,GIRK-4
    Target Alternative Names CIR,Cardiac inward rectifier (CIR),G protein-activated inward rectifier potassium channel 4,GIRK-4,GIRK4,Heart KATP channel,Inward rectifier K(+) channel Kir3.4 (IRK-4),KATP-1,KATP1,KCNJ5,KIR3.4,Kcnj5,Kir3.4,LQT13,Potassium channel,inwardly rectifying subfamily J member 5
    Uniprot Accession F1MYR9,P48544,P48545,P48548
    Additional SwissProt Accessions: P48545,P48548,P48544,F1MYR9
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG Circadian entrainment, Serotonergic synapse, Oxytocin signaling pathway, Aldosterone synthesis and secretion, GnRH secretion, Morphine addiction
    Gene Ensembl ENSECAG00000025007, ENSMUSG00000032034, ENSG00000120457, ENSBTAG00000006902
    Target Classification Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.