Explore PRL3/PTP4A3/PRL-3 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
| Target ID |
GM-T78019
|
| Target Name |
PRL3/PTP4A3/PRL-3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
11156
|
| Gene ID |
100058296 (Equus caballus), 100137722 (Bos taurus), 101096639 (Felis catus), 11156 (Homo sapiens)
19245 (Mus musculus), 362930 (Rattus norvegicus), 606961 (Canis lupus familiaris), 693703 (Macaca mulatta)
|
| Target Alternative Names |
PRL-3,PRL-R,PRL3,PTP4A3,Prl-3,Protein tyrosine phosphatase type IVA 3,Protein-tyrosine phosphatase 4a3,Protein-tyrosine phosphatase of regenerating liver 3 (PRL-3),Ptp4a3,pPtp4a3
|
| Uniprot Accession |
O75365,Q9D658
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000030951, ENSBTAG00000046467, ENSG00000184489, ENSMUSG00000059895, ENSCAFG00845013289, ENSMMUG00000019392
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of PRL3/PTP4A3/PRL-3 cDNA Clones/ORF Plasmid
PRL3/PTP4A3/PRL-3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11156 | Pre-made Human PTP4A3/PRL3/PRL-3 siRNA oligo Duplex | 11156 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362930 | Pre-made Rat Ptp4a3 siRNA oligo Duplex | 362930 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19245 | Pre-made Mouse Ptp4a3/Prl-3/pPtp4a3 siRNA oligo Duplex | 19245 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693703 | Pre-made Cynomolgus/Rhesus macaque PTP4A3 siRNA oligo Duplex | 693703 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096639 | Pre-made Cat/Feline PTP4A3 siRNA oligo Duplex | 101096639 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo606961 | Pre-made Dog/Canine PTP4A3 siRNA oligo Duplex | 606961 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100137722 | Pre-made Bovines/Cattle PTP4A3 siRNA oligo Duplex | 100137722 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058296 | Pre-made Equine/Horse PTP4A3 siRNA oligo Duplex | 100058296 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRL3/PTP4A3/PRL-3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T78019-Ab | Human | Anti-Human PRL3/PTP4A3/PRL-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T78019-Ab | Rat | Anti-Rat PRL3/PTP4A3/PRL-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T78019-Ab | Mouse | Anti-Mouse PRL3/PTP4A3/PRL-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T78019-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRL3/PTP4A3/PRL-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T78019-Ab | Cat/Feline | Anti-Cat/Feline PRL3/PTP4A3/PRL-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T78019-Ab | Dog/Canine | Anti-Dog/Canine PRL3/PTP4A3/PRL-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T78019-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRL3/PTP4A3/PRL-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T78019-Ab | Equine/Horse | Anti-Equine/Horse PRL3/PTP4A3/PRL-3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PRL3/PTP4A3/PRL-3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T78019-Ag | Human | Human PRL3/PTP4A3/PRL-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T78019-Ag | Rat | Rat PRL3/PTP4A3/PRL-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T78019-Ag | Mouse | Mouse PRL3/PTP4A3/PRL-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T78019-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRL3/PTP4A3/PRL-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T78019-Ag | Cat/Feline | Cat/Feline PRL3/PTP4A3/PRL-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T78019-Ag | Dog/Canine | Dog/Canine PRL3/PTP4A3/PRL-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T78019-Ag | Bovines/Cattle | Bovines/Cattle PRL3/PTP4A3/PRL-3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T78019-Ag | Equine/Horse | Equine/Horse PRL3/PTP4A3/PRL-3 recombinant protein | Mammalian cell | Detail |
