Explore PGGT1B/GGTase-I gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
| Target ID |
GM-T76396
|
| Target Name |
PGGT1B/GGTase-I
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5229
|
| Gene ID |
100064254 (Equus caballus), 101089829 (Felis catus), 225467 (Mus musculus), 481440 (Canis lupus familiaris)
509322 (Bos taurus), 5229 (Homo sapiens), 696437 (Macaca mulatta), 81746 (Rattus norvegicus)
|
| Target Alternative Names |
PGGT1B,Pggt1b,BGG1,GGT1,2610100E13,2010207C17Rik,BGGI,GGTI
|
| Uniprot Accession |
Q8BUY9,Q5EAD5,P53609,P53610
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000016179, ENSMUSG00000024477, ENSCAFG00845011236, ENSBTAG00000001895, ENSG00000164219, ENSMMUG00000005018
|
| Target Classification |
|
PGGT1B/GGTase-I siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5229 | Pre-made Human PGGT1B/BGGI/GGTI siRNA oligo Duplex | 5229 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81746 | Pre-made Rat Pggt1b siRNA oligo Duplex | 81746 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo225467 | Pre-made Mouse Pggt1b/BGG1/GGT1 siRNA oligo Duplex | 225467 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696437 | Pre-made Cynomolgus/Rhesus macaque PGGT1B siRNA oligo Duplex | 696437 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089829 | Pre-made Cat/Feline PGGT1B siRNA oligo Duplex | 101089829 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481440 | Pre-made Dog/Canine PGGT1B siRNA oligo Duplex | 481440 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509322 | Pre-made Bovines/Cattle PGGT1B siRNA oligo Duplex | 509322 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064254 | Pre-made Equine/Horse PGGT1B siRNA oligo Duplex | 100064254 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PGGT1B/GGTase-I antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T76396-Ab | Human | Anti-Human PGGT1B/GGTase-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T76396-Ab | Rat | Anti-Rat PGGT1B/GGTase-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T76396-Ab | Mouse | Anti-Mouse PGGT1B/GGTase-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T76396-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PGGT1B/GGTase-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T76396-Ab | Cat/Feline | Anti-Cat/Feline PGGT1B/GGTase-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T76396-Ab | Dog/Canine | Anti-Dog/Canine PGGT1B/GGTase-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T76396-Ab | Bovines/Cattle | Anti-Bovines/Cattle PGGT1B/GGTase-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T76396-Ab | Equine/Horse | Anti-Equine/Horse PGGT1B/GGTase-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PGGT1B/GGTase-I recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T76396-Ag | Human | Human PGGT1B/GGTase-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T76396-Ag | Rat | Rat PGGT1B/GGTase-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T76396-Ag | Mouse | Mouse PGGT1B/GGTase-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T76396-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PGGT1B/GGTase-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T76396-Ag | Cat/Feline | Cat/Feline PGGT1B/GGTase-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T76396-Ag | Dog/Canine | Dog/Canine PGGT1B/GGTase-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T76396-Ag | Bovines/Cattle | Bovines/Cattle PGGT1B/GGTase-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T76396-Ag | Equine/Horse | Equine/Horse PGGT1B/GGTase-I recombinant protein | Mammalian cell | Detail |
