Recombinant multi-species PGGT1B/GGTase-I protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGGT1B/GGTase-I protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
The Alternative Names of target: PGGT1B, GGTase-I,Geranylgeranyl transferase type-1 subunit beta,Geranylgeranyl transferase type I subunit beta (GGTase-I-beta), Type I protein geranyl-geranyltransferase subunit beta,BGGI,GGTI

Target products collectionGo to PGGT1B/GGTase-I products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T76396-Ab-1/ GM-Tg-hg-T76396-Ab-2 Human PGGT1B/GGTase-I protein Human
GM-Tg-rg-T76396-Ab-1/ GM-Tg-rg-T76396-Ab-2 Rat PGGT1B/GGTase-I protein Rat
GM-Tg-mg-T76396-Ab-1/ GM-Tg-mg-T76396-Ab-2 Mouse PGGT1B/GGTase-I protein Mouse
GM-Tg-cynog-T76396-Ab-1/ GM-Tg-cynog-T76396-Ab-2 Cynomolgus/Rhesus macaque PGGT1B/GGTase-I monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T76396-Ab-1/ GM-Tg-felg-T76396-Ab-2 Feline PGGT1B/GGTase-I protein Feline
GM-Tg-cang-T76396-Ab-1/ GM-Tg-cang-T76396-Ab-2 Canine PGGT1B/GGTase-I protein Canine
GM-Tg-bovg-T76396-Ab-1/ GM-Tg-bovg-T76396-Ab-2 Bovine PGGT1B/GGTase-I protein Bovine
GM-Tg-equg-T76396-Ab-1/ GM-Tg-equg-T76396-Ab-2 Equine PGGT1B/GGTase-I protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T76396-Ab-1/ GM-Tg-hg-T76396-Ab-2; GM-Tg-rg-T76396-Ab-1/ GM-Tg-rg-T76396-Ab-2;
GM-Tg-mg-T76396-Ab-1/ GM-Tg-mg-T76396-Ab-2; GM-Tg-cynog-T76396-Ab-1/ GM-Tg-cynog-T76396-Ab-2;
GM-Tg-felg-T76396-Ab-1/ GM-Tg-felg-T76396-Ab-2; GM-Tg-cang-T76396-Ab-1/ GM-Tg-cang-T76396-Ab-2;
GM-Tg-bovg-T76396-Ab-1/ GM-Tg-bovg-T76396-Ab-2; GM-Tg-equg-T76396-Ab-1/ GM-Tg-equg-T76396-Ab-2
Products Name PGGT1B/GGTase-I protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PGGT1B/GGTase-I
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PGGT1B/GGTase-I protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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