Explore AGTR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2020]
| Target ID |
GM-T74456
|
| Target Name |
AGTR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
185
|
| Gene ID |
100059005 (Equus caballus), 101082936 (Felis catus), 11608 (Mus musculus), 185 (Homo sapiens)
281607 (Bos taurus), 403836 (Canis lupus familiaris), 712773 (Macaca mulatta), 81638 (Rattus norvegicus)
|
| Target Alternative Names |
AGTR1,Agtr1b,AT1B,AT2R1B,Agtr-1b,Angtr-1b,AT1,AG2S,AT1R,ATR1,AT1AR,AT1BR,AT2R1,HAT1R,AGTR1B,AT3,Agtr1,AT<sub>1</sub>R
|
| Uniprot Accession |
P29755,P30556,P25104,P43240,P29089
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000001279, ENSMUSG00000054988, ENSG00000144891, ENSBTAG00000045633
|
| Target Classification |
GPCR
|
Pre-made viral vector of AGTR1 cDNA Clones/ORF Plasmid
AGTR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo185 | Pre-made Human AGTR1/AT1/AG2S siRNA oligo Duplex | 185 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81638 | Pre-made Rat Agtr1b/AT1/AT3 siRNA oligo Duplex | 81638 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11608 | Pre-made Mouse Agtr1b/AT1B/AT2R1B siRNA oligo Duplex | 11608 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712773 | Pre-made Cynomolgus/Rhesus macaque AGTR1 siRNA oligo Duplex | 712773 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082936 | Pre-made Cat/Feline AGTR1 siRNA oligo Duplex | 101082936 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403836 | Pre-made Dog/Canine AGTR1/AT1 siRNA oligo Duplex | 403836 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281607 | Pre-made Bovines/Cattle AGTR1 siRNA oligo Duplex | 281607 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059005 | Pre-made Equine/Horse AGTR1 siRNA oligo Duplex | 100059005 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AGTR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T74456-Ab | Human | Anti-Human AGTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T74456-Ab | Rat | Anti-Rat AGTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T74456-Ab | Mouse | Anti-Mouse AGTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T74456-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AGTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T74456-Ab | Cat/Feline | Anti-Cat/Feline AGTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T74456-Ab | Dog/Canine | Anti-Dog/Canine AGTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T74456-Ab | Bovines/Cattle | Anti-Bovines/Cattle AGTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T74456-Ab | Equine/Horse | Anti-Equine/Horse AGTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
AGTR1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T74456-Ag | Human | Human AGTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T74456-Ag | Rat | Rat AGTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T74456-Ag | Mouse | Mouse AGTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T74456-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AGTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T74456-Ag | Cat/Feline | Cat/Feline AGTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T74456-Ag | Dog/Canine | Dog/Canine AGTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T74456-Ag | Bovines/Cattle | Bovines/Cattle AGTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T74456-Ag | Equine/Horse | Equine/Horse AGTR1 VLP (virus-like particle) | HEK293 | Products Developing |
