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Human AGTR1/AG2S/AGTR1B ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_004835.4)
Cat. No.: pGMPC000236
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human AGTR1/AG2S/AGTR1B Non-Viral expression plasmid (overexpression vector) for mouse AGTR1 overexpression in unique cell transient transfection and stable cell line development.
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Product Description
| Catalog ID | pGMPC000236 |
| Gene Name | AGTR1 |
| Accession Number | NM_004835.4 |
| Gene ID | 185 |
| Species | Human |
| Product Type | Mammalian (Non-Viral Vector) plasmid (overexpression) |
| Insert Length | 1185 bp |
| Gene Alias | AG2S,AGTR1B,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,HAT1R |
| Fluorescent Reporter | YFP(YNE) |
| Mammalian Cell Selection | Null |
| Fusion Tag | HA (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGAAGAAAATGAATCACAAGTCAACTGACAGTCCAAAGGCTCCACAGCTCAGAGGAGGTGTATTTGATATAGTGTTTGCAACAAATTCGACCCAGGTGATCAAAATGATTCTCAACTCTTCTACTGAAGATGGTATTAAAAGAATCCAAGATGATTGTCCCAAAGCTGGAAGGCATAATTACATATTTGTCATGATTCCTACTTTATACAGTATCATCTTTGTGGTGGGAATATTTGGAAACAGCTTGGTGGTGATAGTCATTTACTTTTATATGAAGCTGAAGACTGTGGCCAGTGTTTTTCTTTTGAATTTAGCACTGGCTGACTTATGCTTTTTACTGACTTTGCCACTATGGGCTGTCTACACAGCTATGGAATACCGCTGGCCCTTTGGCAATTACCTATGTAAGATTGCTTCAGCCAGCGTCAGTTTCAACCTGTACGCTAGTGTGTTTCTACTCACGTGTCTCAGCATTGATCGATACCTGGCTATTGTTCACCCAATGAAGTCCCGCCTTCGACGCACAATGCTTGTAGCCAAAGTCACCTGCATCATCATTTGGCTGCTGGCAGGCTTGGCCAGTTTGCCAGCTATAATCCATCGAAATGTATTTTTCATTGAGAACACCAATATTACAGTTTGTGCTTTCCATTATGAGTCCCAAAATTCAACCCTCCCGATAGGGCTGGGCCTGACCAAAAATATACTGGGTTTCCTGTTTCCTTTTCTGATCATTCTTACAAGTTATACTCTTATTTGGAAGGCCCTAAAGAAGGCTTATGAAATTCAGAAGAACAAACCAAGAAATGATGATATTTTTAAGATAATTATGGCAATTGTGCTTTTCTTTTTCTTTTCCTGGATTCCCCACCAAATATTCACTTTTCTGGATGTATTGATTCAACTAGGCATCATACGTGACTGTAGAATTGCAGATATTGTGGACACGGCCATGCCTATCACCATTTGTATAGCTTATTTTAACAATTGCCTGAATCCTCTTTTTTATGGCTTTCTGGGGAAAAAATTTAAAAGATATTTTCTCCAGCTTCTAAAATATATTCCCCCAAAAGCCAAATCCCACTCAAACCTTTCAACAAAAATGAGCACGCTTTCCTACCGCCCCTCAGATAATGTAAGCTCATCCACCAAGAAGCCTGCACCATGTTTTGAGGTTGAGTGA |
| ORF Protein Sequence | MKKMNHKSTDSPKAPQLRGGVFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE |
Reference
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-T74456-Ab | Anti-AGTR1/ AG2SB/ AT1 monoclonal antibody |
| Target Antigen | GM-Tg-g-T74456-Ag | AGTR1 VLP (virus-like particle) |
| ORF Viral Vector | pGMLV000160 | Human AGTR1 Lentivirus plasmid |
| ORF Viral Vector | pGMAD000019 | Human AGTR1 Adenovirus plasmid |
| ORF Viral Vector | pGMPC000236 | Human AGTR1 Mammalian (Non-Viral Vector) plasmid |
| ORF Viral Vector | vGMLV000160 | Human AGTR1 Lentivirus particle |
| ORF Viral Vector | vGMAD000019 | Human AGTR1 Adenovirus particle |
Target information
| Target ID | GM-T74456 |
| Target Name | AGTR1 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
185 |
| Gene ID |
100059005 (Equus caballus), 101082936 (Felis catus), 11608 (Mus musculus), 185 (Homo sapiens) 281607 (Bos taurus), 403836 (Canis lupus familiaris), 712773 (Macaca mulatta), 81638 (Rattus norvegicus) |
| Gene Symbols & Synonyms | AGTR1,Agtr1b,AT1B,AT2R1B,Agtr-1b,Angtr-1b,AT1,AG2S,AT1R,ATR1,AT1AR,AT1BR,AT2R1,HAT1R,AGTR1B,AT3,Agtr1,AT<sub>1</sub>R |
| Target Alternative Names | AGTR1,Type-1 angiotensin II receptor,AT1AR, AT1BR, Angiotensin II type-1 receptor (AT1 receptor),AT1,AG2S,AT1B,AT1R,ATR1,AT1AR,AT1BR,AT2R1,HAT1R,AGTR1B |
| Uniprot Accession |
P25104,P29089,P29755,P30556,P43240
Additional SwissProt Accessions: P29755,P30556,P25104,P43240,P29089 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | |
| Disease from KEGG | Calcium signaling pathway, cGMP-PKG signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Renin-angiotensin system, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, AGE-RAGE signaling pathway in diabetic complications, Cushing syndrome, Pathways in cancer |
| Gene Ensembl | ENSECAG00000001279, ENSMUSG00000054988, ENSG00000144891, ENSBTAG00000045633 |
| Target Classification | GPCR |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.