Explore Galectin-3/Galectin 3/LGALS3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]
| Target ID |
GM-T72038
|
| Target Name |
Galectin-3/Galectin 3/LGALS3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3958
|
| Gene ID |
100050367 (Equus caballus), 101081472 (Felis catus), 16854 (Mus musculus), 3958 (Homo sapiens) 404021 (Canis lupus familiaris), 697290 (Macaca mulatta), 786492 (Bos taurus), 83781 (Rattus norvegicus)
|
| Target Alternative Names |
35 kDa lectin,AGE-R3,CBP 35,CBP30,CBP35,Carbohydrate-binding protein 35 (CBP 35),GAL3,GALBP,GALIG,GBP,Gal-3,Galactose-specific lectin 3,Galactoside-binding protein (GALBP),Galectin 3,Galectin-3,IgE-binding protein,L-31,L-34,L31,LGALS2,LGALS3,Laminin-binding protein,Lectin L-29,Lgals3,MAC2,Mac-2,Mac-2 antigen,gal-3,gal3,galectin-3
|
| Uniprot Accession |
P16110,P17931,P38486,P08699
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000006474, ENSMUSG00000050335, ENSG00000131981, ENSCAFG00845015017, ENSMMUG00000003565, ENSBTAG00000002326
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of Galectin-3/Galectin 3/LGALS3 cDNA Clones/ORF Plasmid
Galectin-3/Galectin 3/LGALS3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3958 | Pre-made Human LGALS3/L31/GAL3 siRNA oligo Duplex | 3958 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83781 | Pre-made Rat Lgals3/L-34/CBP30 siRNA oligo Duplex | 83781 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16854 | Pre-made Mouse Lgals3/GBP/L-34 siRNA oligo Duplex | 16854 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697290 | Pre-made Cynomolgus/Rhesus macaque LGALS3 siRNA oligo Duplex | 697290 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081472 | Pre-made Cat/Feline LGALS3 siRNA oligo Duplex | 101081472 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404021 | Pre-made Dog/Canine LGALS3/Gal-3/CBP 35 siRNA oligo Duplex | 404021 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo786492 | Pre-made Bovines/Cattle LGALS3 siRNA oligo Duplex | 786492 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050367 | Pre-made Equine/Horse LGALS3/galectin-3 siRNA oligo Duplex | 100050367 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Galectin-3/Galectin 3/LGALS3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T72038-Ab | Human | Anti-Human Galectin-3/Galectin 3/LGALS3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T72038-Ab | Rat | Anti-Rat Galectin-3/Galectin 3/LGALS3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T72038-Ab | Mouse | Anti-Mouse Galectin-3/Galectin 3/LGALS3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T72038-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Galectin-3/Galectin 3/LGALS3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T72038-Ab | Cat/Feline | Anti-Cat/Feline Galectin-3/Galectin 3/LGALS3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T72038-Ab | Dog/Canine | Anti-Dog/Canine Galectin-3/Galectin 3/LGALS3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T72038-Ab | Bovines/Cattle | Anti-Bovines/Cattle Galectin-3/Galectin 3/LGALS3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T72038-Ab | Equine/Horse | Anti-Equine/Horse Galectin-3/Galectin 3/LGALS3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Galectin-3/Galectin 3/LGALS3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T72038-Ag | Human | Human Galectin-3/Galectin 3/LGALS3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T72038-Ag | Rat | Rat Galectin-3/Galectin 3/LGALS3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T72038-Ag | Mouse | Mouse Galectin-3/Galectin 3/LGALS3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T72038-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Galectin-3/Galectin 3/LGALS3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T72038-Ag | Cat/Feline | Cat/Feline Galectin-3/Galectin 3/LGALS3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T72038-Ag | Dog/Canine | Dog/Canine Galectin-3/Galectin 3/LGALS3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T72038-Ag | Bovines/Cattle | Bovines/Cattle Galectin-3/Galectin 3/LGALS3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T72038-Ag | Equine/Horse | Equine/Horse Galectin-3/Galectin 3/LGALS3 VLP (virus-like particle) | HEK293 | Products Developing |