Complement factor H/CFH Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Complement factor H/CFH gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

Target ID GM-T71086
Target Name Complement factor H/CFH
Gene Group ldentifer
(Target Gene ID in Homo species)
3075
Gene ID 100051358 (Equus caballus), 12628 (Mus musculus), 3075 (Homo sapiens), 478952 (Canis lupus familiaris)
717346 (Macaca mulatta)
Target Alternative Names AHUS1,AMBP1,ARMD4,ARMS1,CFH,CFH-L,CFHL3,Cfh,Complement factor H,FH,FHL1,H factor 1,HF,HF1,HF2,HUS,Mud-1,NOM,Sas-1,Sas1
Uniprot Accession P06909,P08603
Protein Sub-location Secreted Protein/Potential Cytokines
Category Therapeutics Target
Disease Dent disease, Diabetes type-2, Alzheimer's Disease
Disease from KEGG Complement and coagulation cascades, Staphylococcus aureus infection
Gene Ensembl ENSECAG00000011256, ENSMUSG00000026365, ENSG00000000971, ENSCAFG00845029192, ENSMMUG00000045497


Pre-made viral vector of Complement factor H/CFH cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLV002522Human CFH/AHUS1/AMBP1 Lentivirus plasmidNM_001014975.33075HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAD000033Human CFH/AHUS1/AMBP1 Adenovirus plasmidNM_001014975.23075HumanAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
vGMLV002522Human CFH/AHUS1/AMBP1 Lentivirus particleNM_001014975.33075HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000033Human CFH/AHUS1/AMBP1 Adenovirus particleNM_001014975.23075HumanAdenovirus particleNull3xflag (C-Terminal)CMVDetail


Complement factor H/CFH siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3075Pre-made Human CFH/FH/HF siRNA oligo Duplex3075HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo12628Pre-made Mouse Cfh/NOM/Sas1 siRNA oligo Duplex12628MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo717346Pre-made Cynomolgus/Rhesus macaque CFH/CFH-L siRNA oligo Duplex717346Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo478952Pre-made Dog/Canine CFH siRNA oligo Duplex478952Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo100051358Pre-made Equine/Horse CFH siRNA oligo Duplex100051358Equine/HorseIn-vitro grade; in-vivo gradeDetail


Complement factor H/CFH antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T71086-AbHumanAnti-Human Complement factor H/CFH monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T71086-AbMouseAnti-Mouse Complement factor H/CFH monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T71086-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque Complement factor H/CFH monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T71086-AbDog/CanineAnti-Dog/Canine Complement factor H/CFH monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T71086-AbEquine/HorseAnti-Equine/Horse Complement factor H/CFH monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


Complement factor H/CFH recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T71086-AgHumanHuman Complement factor H/CFH recombinant proteinMammalian cellDetail
GM-Tg-mg-T71086-AgMouseMouse Complement factor H/CFH recombinant proteinMammalian cellDetail
GM-Tg-cynog-T71086-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque Complement factor H/CFH recombinant proteinMammalian cellDetail
GM-Tg-cang-T71086-AgDog/CanineDog/Canine Complement factor H/CFH recombinant proteinMammalian cellDetail
GM-Tg-equg-T71086-AgEquine/HorseEquine/Horse Complement factor H/CFH recombinant proteinMammalian cellDetail