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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T71023
|
| Target Name |
SNAP25
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6616
|
| Gene ID |
100051273 (Equus caballus), 101092511 (Felis catus), 20614 (Mus musculus), 25012 (Rattus norvegicus) 477158 (Canis lupus familiaris), 540853 (Bos taurus), 574204 (Macaca mulatta), 6616 (Homo sapiens)
|
| Target Alternative Names |
Bdr,CMS18,GENA70,RIC-4,RIC4,SEC9,SNAP,SNAP-25,SNAP-25B,SNAP-25a,SNAP25,SUP,Snap25,Super protein (SUP),Synaptosomal-associated 25 kDa protein,Synaptosomal-associated protein 25,bA416N4.2,dJ1068F16.2,sp
|
| Uniprot Accession |
P60879,P60881,Q17QQ3,P60877,P60880
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Insulin secretion
|
| Gene Ensembl |
ENSECAG00000023077, ENSMUSG00000027273, ENSCAFG00845024602, ENSBTAG00000008323, ENSMMUG00000011064, ENSG00000132639
|
Pre-made viral vector of SNAP25 cDNA Clones/ORF Plasmid
SNAP25 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6616 | Pre-made Human SNAP25/SUP/RIC4 siRNA oligo Duplex | 6616 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25012 | Pre-made Rat Snap25/SNAP-25B/SNAP-25a siRNA oligo Duplex | 25012 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20614 | Pre-made Mouse Snap25/sp/Bdr siRNA oligo Duplex | 20614 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574204 | Pre-made Cynomolgus/Rhesus macaque SNAP25/SNAP-25 siRNA oligo Duplex | 574204 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092511 | Pre-made Cat/Feline SNAP25 siRNA oligo Duplex | 101092511 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477158 | Pre-made Dog/Canine SNAP25 siRNA oligo Duplex | 477158 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540853 | Pre-made Bovines/Cattle SNAP25/SNAP-25 siRNA oligo Duplex | 540853 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051273 | Pre-made Equine/Horse SNAP25 siRNA oligo Duplex | 100051273 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SNAP25 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T71023-Ab | Human | Anti-Human SNAP25 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T71023-Ab | Rat | Anti-Rat SNAP25 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T71023-Ab | Mouse | Anti-Mouse SNAP25 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T71023-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SNAP25 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T71023-Ab | Cat/Feline | Anti-Cat/Feline SNAP25 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T71023-Ab | Dog/Canine | Anti-Dog/Canine SNAP25 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T71023-Ab | Bovines/Cattle | Anti-Bovines/Cattle SNAP25 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T71023-Ab | Equine/Horse | Anti-Equine/Horse SNAP25 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SNAP25 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T71023-Ag | Human | Human SNAP25 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T71023-Ag | Rat | Rat SNAP25 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T71023-Ag | Mouse | Mouse SNAP25 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T71023-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SNAP25 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T71023-Ag | Cat/Feline | Cat/Feline SNAP25 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T71023-Ag | Dog/Canine | Dog/Canine SNAP25 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T71023-Ag | Bovines/Cattle | Bovines/Cattle SNAP25 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T71023-Ag | Equine/Horse | Equine/Horse SNAP25 VLP (virus-like particle) | HEK293 | Products Developing |