Explore RTN4/NOGO gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T70062
|
| Target Name |
RTN4/NOGO
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
57142
|
| Gene ID |
100066612 (Equus caballus), 101091611 (Felis catus), 359718 (Bos taurus), 474598 (Canis lupus familiaris)
57142 (Homo sapiens), 619181 (Macaca mulatta), 68585 (Mus musculus), 83765 (Rattus norvegicus)
|
| Target Alternative Names |
RTN4,Rtn4,ASY,NSP,NOGO,RTN-X,NSP-CL,RTN4-A,RTN4-C,RTN4-B1,RTN4-B2,NI220/250,Nbla00271,Nbla10545,RTN4-Cw,NgA,Nogo-A,Nogo-B,Nogo-C,mKIAA0886,mKIAA4153,1110020G17Rik,C130026I10Rik,Nogo,Vp20,rat N,NI-250,rat NogoA
|
| Uniprot Accession |
Q9NQC3,Q99P72,Q9JK11
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
|
| Disease from KEGG |
Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000011846, ENSBTAG00000011104, ENSCAFG00845010381, ENSG00000115310, ENSMMUG00000021299, ENSMUSG00000020458
|
| Target Classification |
|
Pre-made viral vector of RTN4/NOGO cDNA Clones/ORF Plasmid
RTN4/NOGO siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo57142 | Pre-made Human RTN4/ASY/NSP siRNA oligo Duplex | 57142 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83765 | Pre-made Rat Rtn4/Nogo/Vp20 siRNA oligo Duplex | 83765 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo68585 | Pre-made Mouse Rtn4/ASY/NgA siRNA oligo Duplex | 68585 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo619181 | Pre-made Cynomolgus/Rhesus macaque RTN4/RTN4-Cw siRNA oligo Duplex | 619181 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091611 | Pre-made Cat/Feline RTN4 siRNA oligo Duplex | 101091611 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474598 | Pre-made Dog/Canine RTN4 siRNA oligo Duplex | 474598 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo359718 | Pre-made Bovines/Cattle RTN4 siRNA oligo Duplex | 359718 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066612 | Pre-made Equine/Horse RTN4 siRNA oligo Duplex | 100066612 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RTN4/NOGO antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T70062-Ab | Human | Anti-Human RTN4/NOGO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T70062-Ab | Rat | Anti-Rat RTN4/NOGO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T70062-Ab | Mouse | Anti-Mouse RTN4/NOGO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T70062-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RTN4/NOGO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T70062-Ab | Cat/Feline | Anti-Cat/Feline RTN4/NOGO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T70062-Ab | Dog/Canine | Anti-Dog/Canine RTN4/NOGO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T70062-Ab | Bovines/Cattle | Anti-Bovines/Cattle RTN4/NOGO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T70062-Ab | Equine/Horse | Anti-Equine/Horse RTN4/NOGO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
RTN4/NOGO VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T70062-Ag | Human | Human RTN4/NOGO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T70062-Ag | Rat | Rat RTN4/NOGO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T70062-Ag | Mouse | Mouse RTN4/NOGO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T70062-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RTN4/NOGO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T70062-Ag | Cat/Feline | Cat/Feline RTN4/NOGO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T70062-Ag | Dog/Canine | Dog/Canine RTN4/NOGO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T70062-Ag | Bovines/Cattle | Bovines/Cattle RTN4/NOGO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T70062-Ag | Equine/Horse | Equine/Horse RTN4/NOGO VLP (virus-like particle) | HEK293 | Products Developing |
