JUN Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein
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Target
sublocation: Introcelluar Protein.
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
| Target ID | GM-T69085 |
| Target Name | JUN |
|
Gene Group ldentifer （Target Gene ID in Homo species) |
3725 |
| Gene ID |
100067469 (Equus caballus), 101097261 (Felis catus), 16476 (Mus musculus), 24516 (Rattus norvegicus) 280831 (Bos taurus), 3725 (Homo sapiens), 609429 (Canis lupus familiaris), 716452 (Macaca mulatta) |
| Target Alternative Names | AP-1,AP1,Activator protein 1 (AP1),JUN,Jun,Junc,Proto-oncogene c-Jun,Transcription factor AP-1 subunit Jun,Transcription factor Jun,V-jun avian sarcoma virus 17 oncogene homolog,c-Jun,c-jun,cJUN,p39 |
| Uniprot Accession | P05627,P17325,O77627,P05412 |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | cancer |
| Disease from KEGG | Endocrine resistance, MAPK signaling pathway, ErbB signaling pathway, cAMP signaling pathway, Apoptosis, Wnt signaling pathway, Osteoclast differentiation, Focal adhesion, Tight junction, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, TNF signaling pathway, Neurotrophin signaling pathway, GnRH signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Cocaine addiction, Amphetamine addiction, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Pertussis, Yersinia infection, Leishmaniasis, Chagas disease, Hepatitis B, Measles, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Renal cell carcinoma, Breast cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease, Rheumatoid arthritis, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis |
| Gene Ensembl | ENSECAG00000024055, ENSMUSG00000052684, ENSG00000177606, ENSCAFG00845006541, ENSMMUG00000059326 |
| Target Classification | Tumor-associated antigen (TAA) |
Pre-made viral vector of JUN cDNA Clones/ORF Plasmid
| Cat No. | Product Name | NMID | GeneID | Species | Type | Marker | Fusion Tag | Promoter | Detail |
|---|---|---|---|---|---|---|---|---|---|
| pGMLP005587 | Human JUN/AP-1/AP1 Lentivirus plasmid | NM_002228.3 | 3725 | Human | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| vGMLP-SPh-129 | Human JUN/AP1/c-Jun Lentivirus particle | BC006175 | 3725 | Human | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| vGMAD000912 | Human JUN/AP-1/AP1 Adenovirus particle | NM_002228.4 | 3725 | Human | Adenovirus particle | EGFP | Null | EF1 | Detail |
| vGMAD000140 | Human JUN/AP-1/AP1 Adenovirus particle | NM_002228.3 | 3725 | Human | Adenovirus particle | GFP | MYC (C-Terminal) | EF1 | Detail |
| vGMLV001471 | Human JUN/AP-1/AP1 Lentivirus particle | NM_002228.4 | 3725 | Human | Lentivirus particle | ZsGreen | Null | CMV | Detail |
| vGMLV000295 | Human JUN/AP-1/AP1 Lentivirus particle | NM_002228.3 | 3725 | Human | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| vGMLP005587 | Human JUN/AP-1/AP1 Lentivirus particle | NM_002228.3 | 3725 | Human | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMLV000295 | Human JUN/AP-1/AP1 Lentivirus plasmid | NM_002228.3 | 3725 | Human | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMPC000142 | Human JUN/AP-1/AP1 Mammalian (Non-Viral Vector) plasmid | NM_002228 | 3725 | Human | Mammalian (Non-Viral Vector) plasmid | Null | Null | CMV | Detail |
| vGMAP000535 | Human JUN/AP1/c-Jun Adenovirus particle | BC006175 | 3725 | Human | Adenovirus particle | GFP | 3xflag (C-Terminal) | EF1 | Detail |
| pGMAP-SPh-269 | Human JUN/AP1/c-Jun Adenovirus plasmid | BC006175 | 3725 | Human | Adenovirus plasmid | EGFP | 3xflag (C-Terminal) | EF1 | Detail |
| pGMLP-SPh-129 | Human JUN/AP1/c-Jun Lentivirus plasmid | BC006175 | 3725 | Human | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMAP000535 | Human JUN/AP1/c-Jun Adenovirus plasmid | BC006175 | 3725 | Human | Adenovirus plasmid | GFP | 3xflag (C-Terminal) | EF1 | Detail |
| vGMAP-SPh-269 | Human JUN/AP1/c-Jun Adenovirus particle | BC006175 | 3725 | Human | Adenovirus particle | EGFP | 3xflag (C-Terminal) | EF1 | Detail |
| pGMAD001483 | Human JUN/AP-1/AP1 Adenovirus plasmid | NM_002228.4 | 3725 | Human | Adenovirus plasmid | EGFP | 3xflag (C-Terminal) | EF1 | Detail |
| pGMAD000912 | Human JUN/AP-1/AP1 Adenovirus plasmid | NM_002228.4 | 3725 | Human | Adenovirus plasmid | EGFP | Null | EF1 | Detail |
| pGMAD000140 | Human JUN/AP-1/AP1 Adenovirus plasmid | NM_002228.3 | 3725 | Human | Adenovirus plasmid | GFP | MYC (C-Terminal) | EF1 | Detail |
| pGMLV001471 | Human JUN/AP-1/AP1 Lentivirus plasmid | NM_002228.4 | 3725 | Human | Lentivirus plasmid | ZsGreen | Null | CMV | Detail |
| vGMAD001483 | Human JUN/AP-1/AP1 Adenovirus particle | NM_002228.4 | 3725 | Human | Adenovirus particle | EGFP | 3xflag (C-Terminal) | EF1 | Detail |
| vGMAAV000691 | Rat Jun Adeno-associate virus(AAV) particle | NM_021835.3 | 24516 | Rat | Adeno-associate virus(AAV) particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMAAV000691 | Rat Jun Adeno-associate virus(AAV) plasmid | NM_021835.3 | 24516 | Rat | Adeno-associate virus(AAV) plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| vGMLV001213 | Rat Jun Lentivirus particle | NM_021835.3 | 24516 | Rat | Lentivirus particle | Null | 3xflag (C-Terminal) | CMV | Detail |
| pGMLV001213 | Rat Jun Lentivirus plasmid | NM_021835.3 | 24516 | Rat | Lentivirus plasmid | Null | 3xflag (C-Terminal) | CMV | Detail |
| vGMLP-SPm-117 | Mouse Jun/AP-1/c-jun Lentivirus particle | NM_010591 | 16476 | Mouse | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMPC001852 | Mouse Jun/AP-1/c-jun Mammalian (Non-Viral Vector) plasmid | NM_010591.2 | 16476 | Mouse | Mammalian (Non-Viral Vector) plasmid | EGFP | 3xflag (C-Terminal) | EF1 | Detail |
| vGMAAV000579 | Mouse Jun/AP-1/c-jun Adeno-associate virus(AAV) particle | NM_010591.2 | 16476 | Mouse | Adeno-associate virus(AAV) particle | mCherry | 3xflag (C-Terminal) | CMV | Detail |
| vGMAAV000054 | Mouse Jun/AP-1/c-jun Adeno-associate virus(AAV) particle | NM_010591.2 | 16476 | Mouse | Adeno-associate virus(AAV) particle | GFP | 3xflag (C-Terminal) | CMV | Detail |
| pGMAP-SPm-244 | Mouse Jun/AP-1/c-jun Adenovirus plasmid | NM_010591 | 16476 | Mouse | Adenovirus plasmid | EGFP | 3xflag (C-Terminal) | EF1 | Detail |
| pGMLP-SPm-117 | Mouse Jun/AP-1/c-jun Lentivirus plasmid | NM_010591 | 16476 | Mouse | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMAAV000579 | Mouse Jun/AP-1/c-jun Adeno-associate virus(AAV) plasmid | NM_010591.2 | 16476 | Mouse | Adeno-associate virus(AAV) plasmid | mCherry | 3xflag (C-Terminal) | CMV | Detail |
| pGMAAV000054 | Mouse Jun/AP-1/c-jun Adeno-associate virus(AAV) plasmid | NM_010591.2 | 16476 | Mouse | Adeno-associate virus(AAV) plasmid | GFP | 3xflag (C-Terminal) | CMV | Detail |
| vGMAP-SPm-244 | Mouse Jun/AP-1/c-jun Adenovirus particle | NM_010591 | 16476 | Mouse | Adenovirus particle | EGFP | 3xflag (C-Terminal) | EF1 | Detail |
JUN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|---|---|---|---|---|
| pGMoligo3725 | Pre-made Human JUN/AP1/p39 siRNA oligo Duplex | 3725 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24516 | Pre-made Rat Jun siRNA oligo Duplex | 24516 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16476 | Pre-made Mouse Jun/AP-1/Junc siRNA oligo Duplex | 16476 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716452 | Pre-made Cynomolgus/Rhesus macaque JUN siRNA oligo Duplex | 716452 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097261 | Pre-made Cat/Feline JUN siRNA oligo Duplex | 101097261 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609429 | Pre-made Dog/Canine JUN/AP-1/c-jun siRNA oligo Duplex | 609429 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280831 | Pre-made Bovines/Cattle JUN siRNA oligo Duplex | 280831 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067469 | Pre-made Equine/Horse JUN siRNA oligo Duplex | 100067469 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
JUN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|---|---|---|---|---|
| GM-Tg-hg-T69085-Ab | Human | Anti-Human JUN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T69085-Ab | Rat | Anti-Rat JUN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T69085-Ab | Mouse | Anti-Mouse JUN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T69085-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque JUN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T69085-Ab | Cat/Feline | Anti-Cat/Feline JUN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T69085-Ab | Dog/Canine | Anti-Dog/Canine JUN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T69085-Ab | Bovines/Cattle | Anti-Bovines/Cattle JUN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T69085-Ab | Equine/Horse | Anti-Equine/Horse JUN monoclonal antibody | mab | Therapeutics Target antibody | Detail |
JUN recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|---|---|---|---|
| GM-Tg-hg-T69085-Ag | Human | Human JUN recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T69085-Ag | Rat | Rat JUN recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T69085-Ag | Mouse | Mouse JUN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T69085-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque JUN recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T69085-Ag | Cat/Feline | Cat/Feline JUN recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T69085-Ag | Dog/Canine | Dog/Canine JUN recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T69085-Ag | Bovines/Cattle | Bovines/Cattle JUN recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T69085-Ag | Equine/Horse | Equine/Horse JUN recombinant protein | Mammalian cell | Detail |