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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011]
| Target ID |
GM-T68877
|
| Target Name |
ID2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3398
|
| Gene ID |
100057240 (Equus caballus), 100686903 (Canis lupus familiaris), 101090256 (Felis catus), 15902 (Mus musculus)
25587 (Rattus norvegicus), 3398 (Homo sapiens), 505025 (Bos taurus), 693394 (Macaca mulatta)
|
| Target Alternative Names |
Ac2-300,Class B basic helix-loop-helix protein 26 (bHLHb26),DNA-binding protein inhibitor ID-2,GIG8,ID2,ID2A,ID2H,Id2,Idb2,Inhibitor of DNA binding 2,Inhibitor of differentiation 2,bHLHb26
|
| Uniprot Accession |
P41136,P41137,Q02363,Q3ZC46
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells
|
| Gene Ensembl |
ENSMUSG00000020644, ENSG00000115738, ENSBTAG00000021187, ENSMMUG00000003237
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of ID2 cDNA Clones/ORF Plasmid
ID2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3398 | Pre-made Human ID2/GIG8/ID2A siRNA oligo Duplex | 3398 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25587 | Pre-made Rat Id2/Ac2-300 siRNA oligo Duplex | 25587 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15902 | Pre-made Mouse Id2/Idb2/bHLHb26 siRNA oligo Duplex | 15902 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693394 | Pre-made Cynomolgus/Rhesus macaque ID2 siRNA oligo Duplex | 693394 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090256 | Pre-made Cat/Feline ID2 siRNA oligo Duplex | 101090256 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100686903 | Pre-made Dog/Canine ID2 siRNA oligo Duplex | 100686903 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505025 | Pre-made Bovines/Cattle ID2 siRNA oligo Duplex | 505025 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057240 | Pre-made Equine/Horse ID2 siRNA oligo Duplex | 100057240 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ID2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T68877-Ab | Human | Anti-Human ID2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T68877-Ab | Rat | Anti-Rat ID2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T68877-Ab | Mouse | Anti-Mouse ID2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T68877-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ID2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T68877-Ab | Cat/Feline | Anti-Cat/Feline ID2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T68877-Ab | Dog/Canine | Anti-Dog/Canine ID2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T68877-Ab | Bovines/Cattle | Anti-Bovines/Cattle ID2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T68877-Ab | Equine/Horse | Anti-Equine/Horse ID2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ID2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T68877-Ag | Human | Human ID2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T68877-Ag | Rat | Rat ID2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T68877-Ag | Mouse | Mouse ID2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T68877-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ID2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T68877-Ag | Cat/Feline | Cat/Feline ID2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T68877-Ag | Dog/Canine | Dog/Canine ID2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T68877-Ag | Bovines/Cattle | Bovines/Cattle ID2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T68877-Ag | Equine/Horse | Equine/Horse ID2 recombinant protein | Mammalian cell | Detail |
