Explore TNFRSF17/BCMA/CD269 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T66693
|
| Target Name |
TNFRSF17/BCMA/CD269
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
608
|
| Gene ID |
100055833 (Equus caballus), 100684674 (Canis lupus familiaris), 101086618 (Felis catus), 101908051 (Bos taurus)
21935 (Mus musculus), 287034 (Rattus norvegicus), 608 (Homo sapiens), 712212 (Macaca mulatta)
|
| Target Alternative Names |
B-cell maturation protein,BCM,BCMA,CD269,TNFRSF13A,TNFRSF17,Tnfrsf13,Tnfrsf13a,Tnfrsf17,Tumor necrosis factor receptor superfamily member 17
|
| Uniprot Accession |
O88472,Q02223
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production
|
| Gene Ensembl |
ENSECAG00000020490, ENSCAFG00845012002, ENSBTAG00000049285, ENSMUSG00000022496, ENSG00000048462, ENSMMUG00000021520
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of TNFRSF17/BCMA/CD269 cDNA Clones/ORF Plasmid
TNFRSF17/BCMA/CD269 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo608 | Pre-made Human TNFRSF17/BCM/BCMA siRNA oligo Duplex | 608 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287034 | Pre-made Rat Tnfrsf17 siRNA oligo Duplex | 287034 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21935 | Pre-made Mouse Tnfrsf17/BCM/BCMA siRNA oligo Duplex | 21935 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712212 | Pre-made Cynomolgus/Rhesus macaque TNFRSF17 siRNA oligo Duplex | 712212 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086618 | Pre-made Cat/Feline TNFRSF17 siRNA oligo Duplex | 101086618 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100684674 | Pre-made Dog/Canine TNFRSF17 siRNA oligo Duplex | 100684674 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101908051 | Pre-made Bovines/Cattle TNFRSF17 siRNA oligo Duplex | 101908051 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055833 | Pre-made Equine/Horse TNFRSF17 siRNA oligo Duplex | 100055833 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TNFRSF17/BCMA/CD269 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T66693-Ab | Human | Anti-Human TNFRSF17/BCMA/CD269 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T66693-Ab | Rat | Anti-Rat TNFRSF17/BCMA/CD269 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T66693-Ab | Mouse | Anti-Mouse TNFRSF17/BCMA/CD269 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T66693-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TNFRSF17/BCMA/CD269 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T66693-Ab | Cat/Feline | Anti-Cat/Feline TNFRSF17/BCMA/CD269 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T66693-Ab | Dog/Canine | Anti-Dog/Canine TNFRSF17/BCMA/CD269 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T66693-Ab | Bovines/Cattle | Anti-Bovines/Cattle TNFRSF17/BCMA/CD269 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T66693-Ab | Equine/Horse | Anti-Equine/Horse TNFRSF17/BCMA/CD269 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
TNFRSF17/BCMA/CD269 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T66693-Ag | Human | Human TNFRSF17/BCMA/CD269 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T66693-Ag | Rat | Rat TNFRSF17/BCMA/CD269 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T66693-Ag | Mouse | Mouse TNFRSF17/BCMA/CD269 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T66693-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TNFRSF17/BCMA/CD269 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T66693-Ag | Cat/Feline | Cat/Feline TNFRSF17/BCMA/CD269 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T66693-Ag | Dog/Canine | Dog/Canine TNFRSF17/BCMA/CD269 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T66693-Ag | Bovines/Cattle | Bovines/Cattle TNFRSF17/BCMA/CD269 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T66693-Ag | Equine/Horse | Equine/Horse TNFRSF17/BCMA/CD269 VLP (virus-like particle) | HEK293 | Products Developing |
