DNMT3B Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore DNMT3B gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]

Target ID GM-T65501
Target Name DNMT3B
Gene Group ldentifer
（Target Gene ID in Homo species) 		1789
Gene ID 100053900 (Equus caballus), 100685634 (Canis lupus familiaris), 101092926 (Felis catus), 13436 (Mus musculus)
1789 (Homo sapiens), 353354 (Bos taurus), 444985 (Rattus norvegicus), 711553 (Macaca mulatta)
Target Alternative Names DNA (cytosine-5)-methyltransferase 3B,DNA methyltransferase HsaIIIB (DNA MTase HsaIIIB,DNMT3B,Dnmt3b,FSHD4,ICF,ICF1,M.HsaIIIB,M.HsaIIIB),MmuIIIB
Uniprot Accession O88509,Q9UBC3
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Metabolic pathways
Gene Ensembl ENSECAG00000012102, ENSCAFG00845022122, ENSMUSG00000027478, ENSG00000088305, ENSBTAG00000003901, ENSMMUG00000019474
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of DNMT3B cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLV002457Human DNMT3B/ICF/ICF1 Lentivirus plasmidNM_006892.31789HumanLentivirus plasmidZsGreenMYC (C-Terminal)CMVDetail
pGMAD000196Human DNMT3B/ICF/ICF1 Adenovirus plasmidNM_006892.31789HumanAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
pGMPC001560Human DNMT3B/ICF/ICF1 Mammalian (Non-Viral Vector) plasmidNM_006892.31789HumanMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLV002457Human DNMT3B/ICF/ICF1 Lentivirus particleNM_006892.31789HumanLentivirus particleZsGreenMYC (C-Terminal)CMVDetail
vGMAD000196Human DNMT3B/ICF/ICF1 Adenovirus particleNM_006892.31789HumanAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
pGMLPm004826Mouse Dnmt3b/MmuIIIB Lentivirus plasmidNM_001271747.113436MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm004826Mouse Dnmt3b/MmuIIIB Lentivirus particleNM_001271747.113436MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


DNMT3B siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo1789Pre-made Human DNMT3B/ICF/ICF1 siRNA oligo Duplex1789HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo444985Pre-made Rat Dnmt3b siRNA oligo Duplex444985RatIn-vitro grade; in-vivo gradeDetail
pGMoligo13436Pre-made Mouse Dnmt3b/MmuIIIB siRNA oligo Duplex13436MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo711553Pre-made Cynomolgus/Rhesus macaque DNMT3B siRNA oligo Duplex711553Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092926Pre-made Cat/Feline DNMT3B siRNA oligo Duplex101092926Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo100685634Pre-made Dog/Canine DNMT3B siRNA oligo Duplex100685634Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo353354Pre-made Bovines/Cattle DNMT3B siRNA oligo Duplex353354Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100053900Pre-made Equine/Horse DNMT3B siRNA oligo Duplex100053900Equine/HorseIn-vitro grade; in-vivo gradeDetail


DNMT3B antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T65501-AbHumanAnti-Human DNMT3B monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T65501-AbRatAnti-Rat DNMT3B monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T65501-AbMouseAnti-Mouse DNMT3B monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T65501-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque DNMT3B monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T65501-AbCat/FelineAnti-Cat/Feline DNMT3B monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T65501-AbDog/CanineAnti-Dog/Canine DNMT3B monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T65501-AbBovines/CattleAnti-Bovines/Cattle DNMT3B monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T65501-AbEquine/HorseAnti-Equine/Horse DNMT3B monoclonal antibodymabTherapeutics Target antibodyDetail


DNMT3B recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T65501-AgHumanHuman DNMT3B recombinant proteinMammalian cellDetail
GM-Tg-rg-T65501-AgRatRat DNMT3B recombinant proteinMammalian cellDetail
GM-Tg-mg-T65501-AgMouseMouse DNMT3B recombinant proteinMammalian cellDetail
GM-Tg-cynog-T65501-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque DNMT3B recombinant proteinMammalian cellDetail
GM-Tg-felg-T65501-AgCat/FelineCat/Feline DNMT3B recombinant proteinMammalian cellDetail
GM-Tg-cang-T65501-AgDog/CanineDog/Canine DNMT3B recombinant proteinMammalian cellDetail
GM-Tg-bovg-T65501-AgBovines/CattleBovines/Cattle DNMT3B recombinant proteinMammalian cellDetail
GM-Tg-equg-T65501-AgEquine/HorseEquine/Horse DNMT3B recombinant proteinMammalian cellDetail