Explore ICOS/CD278 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T62705
|
| Target Name |
ICOS/CD278
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
29851
|
| Gene ID |
100067953 (Equus caballus), 101089031 (Felis catus), 29851 (Homo sapiens), 403456 (Canis lupus familiaris)
507026 (Bos taurus), 54167 (Mus musculus), 64545 (Rattus norvegicus), 705788 (Macaca mulatta)
|
| Target Alternative Names |
AILIM,Activation-inducible lymphocyte immunomediatory molecule,Ailim,CCLP,CD278,CRP-1,CVID1,H4,ICOS,Icos,Inducible T-cell costimulator,Ly115
|
| Uniprot Accession |
Q9Y6W8,Q7YR73,Q58DF9,Q9WVS0,Q9R1T7
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Cell adhesion molecules, T cell receptor signaling pathway, Intestinal immune network for IgA production
|
| Gene Ensembl |
ENSECAG00000006253, ENSG00000163600, ENSCAFG00845018403, ENSBTAG00000021596, ENSMUSG00000026009, ENSMMUG00000002648
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of ICOS/CD278 cDNA Clones/ORF Plasmid
ICOS/CD278 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo29851 | Pre-made Human ICOS/AILIM/CD278 siRNA oligo Duplex | 29851 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64545 | Pre-made Rat Icos/Ailim siRNA oligo Duplex | 64545 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54167 | Pre-made Mouse Icos/H4/CCLP siRNA oligo Duplex | 54167 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705788 | Pre-made Cynomolgus/Rhesus macaque ICOS siRNA oligo Duplex | 705788 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089031 | Pre-made Cat/Feline ICOS siRNA oligo Duplex | 101089031 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403456 | Pre-made Dog/Canine ICOS siRNA oligo Duplex | 403456 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507026 | Pre-made Bovines/Cattle ICOS siRNA oligo Duplex | 507026 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067953 | Pre-made Equine/Horse ICOS siRNA oligo Duplex | 100067953 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ICOS/CD278 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T62705-Ab | Human | Anti-Human ICOS/CD278 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T62705-Ab | Rat | Anti-Rat ICOS/CD278 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T62705-Ab | Mouse | Anti-Mouse ICOS/CD278 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T62705-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ICOS/CD278 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T62705-Ab | Cat/Feline | Anti-Cat/Feline ICOS/CD278 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T62705-Ab | Dog/Canine | Anti-Dog/Canine ICOS/CD278 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T62705-Ab | Bovines/Cattle | Anti-Bovines/Cattle ICOS/CD278 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T62705-Ab | Equine/Horse | Anti-Equine/Horse ICOS/CD278 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ICOS/CD278 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T62705-Ag | Human | Human ICOS/CD278 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T62705-Ag | Rat | Rat ICOS/CD278 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T62705-Ag | Mouse | Mouse ICOS/CD278 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T62705-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ICOS/CD278 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T62705-Ag | Cat/Feline | Cat/Feline ICOS/CD278 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T62705-Ag | Dog/Canine | Dog/Canine ICOS/CD278 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T62705-Ag | Bovines/Cattle | Bovines/Cattle ICOS/CD278 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T62705-Ag | Equine/Horse | Equine/Horse ICOS/CD278 VLP (virus-like particle) | HEK293 | Products Developing |
