Explore CD1A/CD1a gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
| Target ID |
GM-T60433
|
| Target Name |
CD1A/CD1a
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
909
|
| Gene ID |
100054902 (Equus caballus), 698438 (Macaca mulatta), 909 (Homo sapiens)
|
| Target Alternative Names |
CD1,CD1A,CD1A1,CD1a,FCB6,HTA1,R4,T-cell surface antigen T6/Leu-6 (hTa1 thymocyte antigen),T-cell surface glycoprotein CD1a,T6
|
| Uniprot Accession |
P06126
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
Tight junction, Hematopoietic cell lineage, Amoebiasis
|
| Gene Ensembl |
ENSECAG00000037237, ENSMMUG00000062253, ENSG00000158477
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of CD1A/CD1a cDNA Clones/ORF Plasmid
CD1A/CD1a siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo909 | Pre-made Human CD1A/R4/T6 siRNA oligo Duplex | 909 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698438 | Pre-made Cynomolgus/Rhesus macaque CD1A siRNA oligo Duplex | 698438 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054902 | Pre-made Equine/Horse CD1A/CD1A1 siRNA oligo Duplex | 100054902 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD1A/CD1a antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T60433-Ab | Human | Anti-Human CD1A/CD1a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T60433-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD1A/CD1a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T60433-Ab | Equine/Horse | Anti-Equine/Horse CD1A/CD1a monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD1A/CD1a VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T60433-Ag | Human | Human CD1A/CD1a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T60433-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD1A/CD1a VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T60433-Ag | Equine/Horse | Equine/Horse CD1A/CD1a VLP (virus-like particle) | HEK293 | Products Developing |
