Explore BDKRB1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene belongs to the G-protein coupled receptor 1 family. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq, Aug 2020]
| Target ID |
GM-T58589
|
| Target Name |
BDKRB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
623
|
| Gene ID |
100054699 (Equus caballus), 12061 (Mus musculus), 490847 (Canis lupus familiaris), 532119 (Bos taurus)
623 (Homo sapiens), 712251 (Macaca mulatta), 81509 (Rattus norvegicus)
|
| Target Alternative Names |
B1 bradykinin receptor,B1BKR,B1R,BDKRB1,BK-1 receptor,BKB1R,BKR,BKR1,BRADYB1,Bdkrb,Bdkrb1,b1bkr
|
| Uniprot Accession |
Q61125,Q9BDQ5,P46663,Q8HZP2,P97583
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000005631, ENSMUSG00000041347, ENSCAFG00845003563, ENSG00000100739
|
| Target Classification |
GPCR
|
Pre-made viral vector of BDKRB1 cDNA Clones/ORF Plasmid
BDKRB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo623 | Pre-made Human BDKRB1/B1R/BKR1 siRNA oligo Duplex | 623 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81509 | Pre-made Rat Bdkrb1/BKR/Bdkrb siRNA oligo Duplex | 81509 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12061 | Pre-made Mouse Bdkrb1/B1R/BKR1 siRNA oligo Duplex | 12061 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712251 | Pre-made Cynomolgus/Rhesus macaque BDKRB1/B1R siRNA oligo Duplex | 712251 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490847 | Pre-made Dog/Canine BDKRB1 siRNA oligo Duplex | 490847 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532119 | Pre-made Bovines/Cattle BDKRB1 siRNA oligo Duplex | 532119 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054699 | Pre-made Equine/Horse BDKRB1 siRNA oligo Duplex | 100054699 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BDKRB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T58589-Ab | Human | Anti-Human BDKRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T58589-Ab | Rat | Anti-Rat BDKRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T58589-Ab | Mouse | Anti-Mouse BDKRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T58589-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BDKRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T58589-Ab | Dog/Canine | Anti-Dog/Canine BDKRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T58589-Ab | Bovines/Cattle | Anti-Bovines/Cattle BDKRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T58589-Ab | Equine/Horse | Anti-Equine/Horse BDKRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
BDKRB1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T58589-Ag | Human | Human BDKRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T58589-Ag | Rat | Rat BDKRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T58589-Ag | Mouse | Mouse BDKRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T58589-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BDKRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T58589-Ag | Dog/Canine | Dog/Canine BDKRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T58589-Ag | Bovines/Cattle | Bovines/Cattle BDKRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T58589-Ag | Equine/Horse | Equine/Horse BDKRB1 VLP (virus-like particle) | HEK293 | Products Developing |
