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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018]
| Target ID |
GM-T57050
|
| Target Name |
ZUP1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
221302
|
| Gene ID |
100067070 (Equus caballus), 101092115 (Felis catus), 221302 (Homo sapiens), 294390 (Rattus norvegicus)
476272 (Canis lupus familiaris), 533724 (Bos taurus), 718059 (Macaca mulatta), 72580 (Mus musculus)
|
| Target Alternative Names |
2700019D07Rik,C6orf113,C9H6orf113,DUB,Lys-63-specific deubiquitinase ZUFSP (DUB),RGD1307672,ZUFSP,ZUP1,Zinc finger with UFM1-specific peptidase domain protein,Zinc finger-containing ubiquitin peptidase 1,Zufsp,Zup1
|
| Uniprot Accession |
Q96AP4,Q5U2S3,Q3SWY8,Q3T9Z9
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000013523, ENSG00000153975, ENSCAFG00845005699, ENSBTAG00000003878, ENSMMUG00000001806, ENSMUSG00000039531
|
| Target Classification |
|
ZUP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo221302 | Pre-made Human ZUP1/DUB/ZUFSP siRNA oligo Duplex | 221302 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294390 | Pre-made Rat Zup1/DUB/Zufsp siRNA oligo Duplex | 294390 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo72580 | Pre-made Mouse Zup1/DUB/Zufsp siRNA oligo Duplex | 72580 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718059 | Pre-made Cynomolgus/Rhesus macaque ZUP1/ZUFSP siRNA oligo Duplex | 718059 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092115 | Pre-made Cat/Feline ZUP1/ZUFSP siRNA oligo Duplex | 101092115 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476272 | Pre-made Dog/Canine ZUP1/ZUFSP siRNA oligo Duplex | 476272 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533724 | Pre-made Bovines/Cattle ZUP1/DUB/ZUFSP siRNA oligo Duplex | 533724 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067070 | Pre-made Equine/Horse ZUP1/ZUFSP siRNA oligo Duplex | 100067070 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ZUP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T57050-Ab | Human | Anti-Human ZUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T57050-Ab | Rat | Anti-Rat ZUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T57050-Ab | Mouse | Anti-Mouse ZUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T57050-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ZUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T57050-Ab | Cat/Feline | Anti-Cat/Feline ZUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T57050-Ab | Dog/Canine | Anti-Dog/Canine ZUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T57050-Ab | Bovines/Cattle | Anti-Bovines/Cattle ZUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T57050-Ab | Equine/Horse | Anti-Equine/Horse ZUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ZUP1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T57050-Ag | Human | Human ZUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T57050-Ag | Rat | Rat ZUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T57050-Ag | Mouse | Mouse ZUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T57050-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ZUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T57050-Ag | Cat/Feline | Cat/Feline ZUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T57050-Ag | Dog/Canine | Dog/Canine ZUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T57050-Ag | Bovines/Cattle | Bovines/Cattle ZUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T57050-Ag | Equine/Horse | Equine/Horse ZUP1 recombinant protein | Mammalian cell | Detail |
