Recombinant multi-species ZUP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ZUP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018]
The Alternative Names of target: 2700019D07Rik,C6orf113,C9H6orf113,DUB,Lys-63-specific deubiquitinase ZUFSP (DUB),RGD1307672,ZUFSP,ZUP1,Zinc finger with UFM1-specific peptidase domain protein,Zinc finger-containing ubiquitin peptidase 1,Zufsp,Zup1
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T57050-Ag-1/ GM-Tg-hg-T57050-Ag-2 | Human ZUP1 protein | Human |
GM-Tg-rg-T57050-Ag-1/ GM-Tg-rg-T57050-Ag-2 | Rat ZUP1 protein | Rat |
GM-Tg-mg-T57050-Ag-1/ GM-Tg-mg-T57050-Ag-2 | Mouse ZUP1 protein | Mouse |
GM-Tg-cynog-T57050-Ag-1/ GM-Tg-cynog-T57050-Ag-2 | Cynomolgus/Rhesus macaque ZUP1 protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T57050-Ag-1/ GM-Tg-felg-T57050-Ag-2 | Feline ZUP1 protein | Feline |
GM-Tg-cang-T57050-Ag-1/ GM-Tg-cang-T57050-Ag-2 | Canine ZUP1 protein | Canine |
GM-Tg-bovg-T57050-Ag-1/ GM-Tg-bovg-T57050-Ag-2 | Bovine ZUP1 protein | Bovine |
GM-Tg-equg-T57050-Ag-1/ GM-Tg-equg-T57050-Ag-2 | Equine ZUP1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T57050-Ag-1/ GM-Tg-hg-T57050-Ag-2;
GM-Tg-rg-T57050-Ag-1/ GM-Tg-rg-T57050-Ag-2;
GM-Tg-mg-T57050-Ag-1/ GM-Tg-mg-T57050-Ag-2; GM-Tg-cynog-T57050-Ag-1/ GM-Tg-cynog-T57050-Ag-2; GM-Tg-felg-T57050-Ag-1/ GM-Tg-felg-T57050-Ag-2; GM-Tg-cang-T57050-Ag-1/ GM-Tg-cang-T57050-Ag-2; GM-Tg-bovg-T57050-Ag-1/ GM-Tg-bovg-T57050-Ag-2; GM-Tg-equg-T57050-Ag-1/ GM-Tg-equg-T57050-Ag-2 |
Products Name | ZUP1 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | ZUP1 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ZUP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.