Explore KDM5B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
| Target ID |
GM-T56871
|
| Target Name |
KDM5B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10765
|
| Gene ID |
100064707 (Equus caballus), 101101609 (Felis catus), 10765 (Homo sapiens), 304809 (Rattus norvegicus)
479999 (Canis lupus familiaris), 540633 (Bos taurus), 706437 (Macaca mulatta), 75605 (Mus musculus)
|
| Target Alternative Names |
2010009J12Rik,2210016I17Rik,CT31,Cancer/testis antigen 31 (CT31),D1Ertd202e,Histone demethylase JARID1B,JARID1B,Jarid1b,Jumonji/ARID domain-containing protein 1B,KDM5B,Kdm5b,Lysine-specific demethylase 5B,MRT65,PLU-1,PLU1,PPP1R98,PUT1,Plu1,RBBP2H1A,RBP2-H1,RGD1565602,Rb-Bp2,Retinoblastoma-binding protein 2 homolog 1 (RBP2-H1),[histone H3]-trimethyl-L-lysine(4) demethylase 5B,mKIAA4034
|
| Uniprot Accession |
Q9UGL1,Q80Y84
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000014268, ENSG00000117139, ENSCAFG00845014886, ENSBTAG00000006175, ENSMMUG00000015233, ENSMUSG00000042207
|
KDM5B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10765 | Pre-made Human KDM5B/CT31/PLU1 siRNA oligo Duplex | 10765 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo304809 | Pre-made Rat Kdm5b/Jarid1b/RGD1565602 siRNA oligo Duplex | 304809 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo75605 | Pre-made Mouse Kdm5b/PUT1/Plu1 siRNA oligo Duplex | 75605 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706437 | Pre-made Cynomolgus/Rhesus macaque KDM5B siRNA oligo Duplex | 706437 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101609 | Pre-made Cat/Feline KDM5B siRNA oligo Duplex | 101101609 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479999 | Pre-made Dog/Canine KDM5B/JARID1B siRNA oligo Duplex | 479999 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540633 | Pre-made Bovines/Cattle KDM5B/JARID1B siRNA oligo Duplex | 540633 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064707 | Pre-made Equine/Horse KDM5B siRNA oligo Duplex | 100064707 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KDM5B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T56871-Ab | Human | Anti-Human KDM5B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T56871-Ab | Rat | Anti-Rat KDM5B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T56871-Ab | Mouse | Anti-Mouse KDM5B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T56871-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KDM5B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T56871-Ab | Cat/Feline | Anti-Cat/Feline KDM5B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T56871-Ab | Dog/Canine | Anti-Dog/Canine KDM5B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T56871-Ab | Bovines/Cattle | Anti-Bovines/Cattle KDM5B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T56871-Ab | Equine/Horse | Anti-Equine/Horse KDM5B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
KDM5B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T56871-Ag | Human | Human KDM5B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T56871-Ag | Rat | Rat KDM5B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T56871-Ag | Mouse | Mouse KDM5B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T56871-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KDM5B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T56871-Ag | Cat/Feline | Cat/Feline KDM5B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T56871-Ag | Dog/Canine | Dog/Canine KDM5B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T56871-Ag | Bovines/Cattle | Bovines/Cattle KDM5B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T56871-Ag | Equine/Horse | Equine/Horse KDM5B recombinant protein | Mammalian cell | Detail |
