Apolipoprotein AI/APOA1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Apolipoprotein AI/APOA1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]

Target ID GM-T56545
Target Name Apolipoprotein AI/APOA1
Gene Group ldentifer
(Target Gene ID in Homo species)
335
Gene ID 100062583 (Equus caballus), 101081076 (Felis catus), 11806 (Mus musculus), 25081 (Rattus norvegicus)
281631 (Bos taurus), 335 (Homo sapiens), 479427 (Canis lupus familiaris), 696969 (Macaca mulatta)
Target Alternative Names AMYLD3,APOA1,Alp-1,Apo-AI,ApoA-I,Apoa-1,Apoa1,Apolipoprotein A-I,Apolipoprotein A1,Apolipoprotein AI,Brp-14,HPALP2,Ltw-1,Lvtw-1,Sep-1,Sep-2,Sep2,apo(a),apo-AI,apoA-I
Uniprot Accession Q00623,P04639,P15497,P02647,P02648,F7FQM7
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease Ovary Cancer, Ovarian Cancer, Malignant neoplasm of bladder, Nephrotic syndrome, Nephrotic syndrome with focal and segmental glomerular lesions, Type 1 diabetes mellitus, Dent disease, Diabetic Nephropathy
Disease from KEGG PPAR signaling pathway, Fat digestion and absorption, Vitamin digestion and absorption, Cholesterol metabolism, African trypanosomiasis, Lipid and atherosclerosis
Gene Ensembl ENSECAG00000009752, ENSMUSG00000032083, ENSBTAG00000065859, ENSG00000118137, ENSCAFG00845004266, ENSMMUG00000044545


Pre-made viral vector of Apolipoprotein AI/APOA1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMAAV001259Human APOA1/apo(a)/HPALP2 Adeno-associate virus(AAV) plasmidNM_000039.3335HumanAdeno-associate virus(AAV) plasmidZsGreenNullCMVDetail
pGMAP000043Human APOA1 Adenovirus plasmidBC005380335HumanAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
pGMPC000928Human APOA1/apo(a)/HPALP2 Mammalian (Non-Viral Vector) plasmidNM_000039.3335HumanMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAAV001259Human APOA1/apo(a)/HPALP2 Adeno-associate virus(AAV) particleNM_000039.3335HumanAdeno-associate virus(AAV) particleZsGreenNullCMVDetail
vGMAP000043Human APOA1 Adenovirus particleBC005380335HumanAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
pGMLPm000336Mouse Apoa1/Alp-1/apo-AI Lentivirus plasmidNM_00969211806MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm000336Mouse Apoa1/Alp-1/apo-AI Lentivirus particleNM_00969211806MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


Apolipoprotein AI/APOA1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo335Pre-made Human APOA1/AMYLD3/HPALP2 siRNA oligo Duplex335HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo25081Pre-made Rat Apoa1/apoA-I siRNA oligo Duplex25081RatIn-vitro grade; in-vivo gradeDetail
pGMoligo11806Pre-made Mouse Apoa1/Sep2/Alp-1 siRNA oligo Duplex11806MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo696969Pre-made Cynomolgus/Rhesus macaque APOA1/Apo-AI/ApoA-I siRNA oligo Duplex696969Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101081076Pre-made Cat/Feline APOA1 siRNA oligo Duplex101081076Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo479427Pre-made Dog/Canine APOA1/Apo-AI/ApoA-I siRNA oligo Duplex479427Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo281631Pre-made Bovines/Cattle APOA1 siRNA oligo Duplex281631Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100062583Pre-made Equine/Horse APOA1 siRNA oligo Duplex100062583Equine/HorseIn-vitro grade; in-vivo gradeDetail


Apolipoprotein AI/APOA1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T56545-AbHumanAnti-Human Apolipoprotein AI/APOA1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T56545-AbRatAnti-Rat Apolipoprotein AI/APOA1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T56545-AbMouseAnti-Mouse Apolipoprotein AI/APOA1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T56545-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque Apolipoprotein AI/APOA1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T56545-AbCat/FelineAnti-Cat/Feline Apolipoprotein AI/APOA1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T56545-AbDog/CanineAnti-Dog/Canine Apolipoprotein AI/APOA1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T56545-AbBovines/CattleAnti-Bovines/Cattle Apolipoprotein AI/APOA1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T56545-AbEquine/HorseAnti-Equine/Horse Apolipoprotein AI/APOA1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


Apolipoprotein AI/APOA1 VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T56545-AgHumanHuman Apolipoprotein AI/APOA1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T56545-AgRatRat Apolipoprotein AI/APOA1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T56545-AgMouseMouse Apolipoprotein AI/APOA1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T56545-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque Apolipoprotein AI/APOA1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T56545-AgCat/FelineCat/Feline Apolipoprotein AI/APOA1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T56545-AgDog/CanineDog/Canine Apolipoprotein AI/APOA1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T56545-AgBovines/CattleBovines/Cattle Apolipoprotein AI/APOA1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T56545-AgEquine/HorseEquine/Horse Apolipoprotein AI/APOA1 VLP (virus-like particle)HEK293Products Developing