NR1H4/FXR Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore NR1H4/FXR gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]

Target ID GM-T51426
Target Name NR1H4/FXR
Gene Group ldentifer
（Target Gene ID in Homo species) 		9971
Gene ID 100052821 (Equus caballus), 101096997 (Felis catus), 20186 (Mus musculus), 540528 (Bos taurus)
60351 (Rattus norvegicus), 612928 (Canis lupus familiaris), 695618 (Macaca mulatta), 9971 (Homo sapiens)
Target Alternative Names BAR,Bile acid receptor,FXR,Farnesoid X-activated receptor,Farnesol receptor HRR-1,Fxr,HRR-1,HRR1,NR1H4,Nr1h4,Nuclear receptor subfamily 1 group H member 4,PFIC5,RIP14,Retinoid X receptor-interacting protein 14 (RXR-interacting protein 14),Rxrip14
Uniprot Accession Q60641,Q3SZL0,Q62735,Q96RI1
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease from KEGG Bile secretion
Gene Ensembl ENSECAG00000018166, ENSMUSG00000047638, ENSBTAG00000013596, ENSCAFG00845006398, ENSMMUG00000003571, ENSG00000012504
Target Classification Nuclear Receptors


Pre-made viral vector of NR1H4/FXR cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLV001593Human NR1H4/BAR/FXR Lentivirus plasmidNM_0012069799971HumanLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
vGMLV002444Human NR1H4/BAR/FXR Lentivirus particleNM_001206979.29971HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLV002038Human NR1H4/BAR/FXR Lentivirus plasmidNM_0012069799971HumanLentivirus plasmidmCherry3xflag (C-Terminal)CMVDetail
pGMLV002444Human NR1H4/BAR/FXR Lentivirus plasmidNM_001206979.29971HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAD001310Human NR1H4/BAR/FXR Adenovirus plasmidNM_001206993.29971HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAD001310Human NR1H4/BAR/FXR Adenovirus particleNM_001206993.29971HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMLV001799Human NR1H4/BAR/FXR Lentivirus plasmidNM_0012069799971HumanLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
vGMLV001593Human NR1H4/BAR/FXR Lentivirus particleNM_0012069799971HumanLentivirus particleNull3xflag (C-Terminal)CMVDetail
vGMLV001799Human NR1H4/BAR/FXR Lentivirus particleNM_0012069799971HumanLentivirus particleNull3xflag (C-Terminal)CMVDetail
vGMLV002038Human NR1H4/BAR/FXR Lentivirus particleNM_0012069799971HumanLentivirus particlemCherry3xflag (C-Terminal)CMVDetail
vGMAAV000319Mouse Nr1h4/AI957360/Fxr Adeno-associate virus(AAV) particleNM_001163700.120186MouseAdeno-associate virus(AAV) particleGFP3xflag (C-Terminal)CMVDetail
vGMAAV000015Mouse Nr1h4/AI957360/Fxr Adeno-associate virus(AAV) particleNM_001163700.120186MouseAdeno-associate virus(AAV) particleGFP3xflag (C-Terminal)CMVDetail
vGMAD000635Mouse Nr1h4/AI957360/Fxr Adenovirus particleNM_00116370020186MouseAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
pGMPC001475Mouse Nr1h4/Fxr/HRR1 Mammalian (Non-Viral Vector) plasmidNM_001163700.120186MouseMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMAAV000522Mouse Nr1h4/AI957360/Fxr Adeno-associate virus(AAV) plasmidNM_001163700.120186MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV000319Mouse Nr1h4/AI957360/Fxr Adeno-associate virus(AAV) plasmidNM_001163700.120186MouseAdeno-associate virus(AAV) plasmidGFP3xflag (C-Terminal)CMVDetail
pGMAAV000015Mouse Nr1h4/AI957360/Fxr Adeno-associate virus(AAV) plasmidNM_001163700.120186MouseAdeno-associate virus(AAV) plasmidGFP3xflag (C-Terminal)CMVDetail
pGMAD000635Mouse Nr1h4/AI957360/Fxr Adenovirus plasmidNM_00116370020186MouseAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMAAV000522Mouse Nr1h4/AI957360/Fxr Adeno-associate virus(AAV) particleNM_001163700.120186MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail


NR1H4/FXR siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo9971Pre-made Human NR1H4/BAR/FXR siRNA oligo Duplex9971HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo60351Pre-made Rat Nr1h4/Fxr siRNA oligo Duplex60351RatIn-vitro grade; in-vivo gradeDetail
pGMoligo20186Pre-made Mouse Nr1h4/Fxr/HRR1 siRNA oligo Duplex20186MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo695618Pre-made Cynomolgus/Rhesus macaque NR1H4 siRNA oligo Duplex695618Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101096997Pre-made Cat/Feline NR1H4 siRNA oligo Duplex101096997Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo612928Pre-made Dog/Canine NR1H4 siRNA oligo Duplex612928Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo540528Pre-made Bovines/Cattle NR1H4 siRNA oligo Duplex540528Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100052821Pre-made Equine/Horse NR1H4 siRNA oligo Duplex100052821Equine/HorseIn-vitro grade; in-vivo gradeDetail


NR1H4/FXR antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T51426-AbHumanAnti-Human NR1H4/FXR monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T51426-AbRatAnti-Rat NR1H4/FXR monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T51426-AbMouseAnti-Mouse NR1H4/FXR monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T51426-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque NR1H4/FXR monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T51426-AbCat/FelineAnti-Cat/Feline NR1H4/FXR monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T51426-AbDog/CanineAnti-Dog/Canine NR1H4/FXR monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T51426-AbBovines/CattleAnti-Bovines/Cattle NR1H4/FXR monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T51426-AbEquine/HorseAnti-Equine/Horse NR1H4/FXR monoclonal antibodymabTherapeutics Target antibodyDetail


NR1H4/FXR recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T51426-AgHumanHuman NR1H4/FXR recombinant proteinMammalian cellDetail
GM-Tg-rg-T51426-AgRatRat NR1H4/FXR recombinant proteinMammalian cellDetail
GM-Tg-mg-T51426-AgMouseMouse NR1H4/FXR recombinant proteinMammalian cellDetail
GM-Tg-cynog-T51426-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque NR1H4/FXR recombinant proteinMammalian cellDetail
GM-Tg-felg-T51426-AgCat/FelineCat/Feline NR1H4/FXR recombinant proteinMammalian cellDetail
GM-Tg-cang-T51426-AgDog/CanineDog/Canine NR1H4/FXR recombinant proteinMammalian cellDetail
GM-Tg-bovg-T51426-AgBovines/CattleBovines/Cattle NR1H4/FXR recombinant proteinMammalian cellDetail
GM-Tg-equg-T51426-AgEquine/HorseEquine/Horse NR1H4/FXR recombinant proteinMammalian cellDetail