Human NR1H4/BAR/FXR ORF/cDNA clone-Lentivirus plasmid (NM_001206979)

Cat. No.: pGMLV002038
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human NR1H4/BAR/FXR Lentiviral expression plasmid for NR1H4 lentivirus packaging, NR1H4 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV002038
Gene Name NR1H4
Accession Number NM_001206979
Gene ID 9971
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1431 bp
Gene Alias BAR,FXR,HRR-1,HRR1,PFIC5,RIP14
Fluorescent Reporter mCherry
Mammalian Cell Selection Blasticidin (BSD)
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGGATCAAAAATGAATCTCATTGAACATTCCCATTTACCTACCACAGATGAATTTTCTTTTTCTGAAAATTTATTTGGTGTTTTAACAGAACAAGTGGCAGGTCCTCTGGGACAGAACCTGGAAGTGGAACCATACTCGCAATACAGCAATGTTCAGTTTCCCCAAGTTCAACCACAGATTTCCTCGTCATCCTATTATTCCAACCTGGGTTTCTACCCCCAGCAGCCTGAAGAGTGGTACTCTCCTGGAATATATGAACTCAGGCGTATGCCAGCTGAGACTCTCTACCAGGGAGAAACTGAGGTAGCAGAGATGCCTGTAACAAAGAAGCCCCGCATGGGCGCGTCAGCAGGGAGGATCAAAGGGGATGAGCTGTGTGTTGTTTGTGGAGACAGAGCCTCTGGATACCACTATAATGCACTGACCTGTGAGGGGTGTAAAGGTTTCTTCAGGAGAAGCATTACCAAAAACGCTGTGTACAAGTGTAAAAACGGGGGCAACTGTGTGATGGATATGTACATGCGAAGAAAGTGTCAAGAGTGTCGACTAAGGAAATGCAAAGAGATGGGAATGTTGGCTGAATGTATGTATACAGGCTTGTTAACTGAAATTCAGTGTAAATCTAAGCGACTGAGAAAAAATGTGAAGCAGCATGCAGATCAGACCGTGAATGAAGACAGTGAAGGTCGTGACTTGCGACAAGTGACCTCGACAACAAAGTCATGCAGGGAGAAAACTGAACTCACCCCAGATCAACAGACTCTTCTACATTTTATTATGGATTCATATAACAAACAGAGGATGCCTCAGGAAATAACAAATAAAATTTTAAAAGAAGAATTCAGTGCAGAAGAAAATTTTCTCATTTTGACGGAAATGGCAACCAATCATGTACAGGTTCTTGTAGAATTCACAAAAAAGCTACCAGGATTTCAGACTTTGGACCATGAAGACCAGATTGCTTTGCTGAAAGGGTCTGCGGTTGAAGCTATGTTCCTTCGTTCAGCTGAGATTTTCAATAAGAAACTTCCGTCTGGGCATTCTGACCTATTGGAAGAAAGAATTCGAAATAGTGGTATCTCTGATGAATATATAACACCTATGTTTAGTTTTTATAAAAGTATTGGGGAACTGAAAATGACTCAAGAGGAGTATGCTCTGCTTACAGCAATTGTTATCCTGTCTCCAGATAGACAATACATAAAGGATAGAGAGGCAGTAGAGAAGCTTCAGGAGCCACTTCTTGATGTGCTACAAAAGTTGTGTAAGATTCACCAGCCTGAAAATCCTCAACACTTTGCCTGTCTCCTGGGTCGCCTGACTGAATTACGGACATTCAATCATCACCACGCTGAGATGCTGATGTCATGGAGAGTAAACGACCACAAGTTTACCCCACTTCTCTGTGAAATCTGGGACGTGCAGTGA
ORF Protein Sequence MGSKMNLIEHSHLPTTDEFSFSENLFGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T51426-Ab Anti-FXR monoclonal antibody
    Target Antigen GM-Tg-g-T51426-Ag FXR/NR1H4 protein
    ORF Viral Vector pGMLV001593 Human NR1H4 Lentivirus plasmid
    ORF Viral Vector pGMLV001799 Human NR1H4 Lentivirus plasmid
    ORF Viral Vector pGMLV002038 Human NR1H4 Lentivirus plasmid
    ORF Viral Vector pGMLV002444 Human NR1H4 Lentivirus plasmid
    ORF Viral Vector pGMAD001310 Human NR1H4 Adenovirus plasmid
    ORF Viral Vector vGMLV001593 Human NR1H4 Lentivirus particle
    ORF Viral Vector vGMLV001799 Human NR1H4 Lentivirus particle
    ORF Viral Vector vGMLV002038 Human NR1H4 Lentivirus particle
    ORF Viral Vector vGMLV002444 Human NR1H4 Lentivirus particle
    ORF Viral Vector vGMAD001310 Human NR1H4 Adenovirus particle


    Target information

    Target ID GM-T51426
    Target Name NR1H4/FXR
    Gene Group Identifier
    （Target Gene ID in Homo species)         		9971
    Gene ID 100052821 (Equus caballus), 101096997 (Felis catus), 20186 (Mus musculus), 540528 (Bos taurus)
    60351 (Rattus norvegicus), 612928 (Canis lupus familiaris), 695618 (Macaca mulatta), 9971 (Homo sapiens)
    Gene Symbols & Synonyms NR1H4,Nr1h4,Fxr,HRR1,RIP14,Rxrip14,BAR,FXR,HRR-1,PFIC5
    Target Alternative Names BAR,Bile acid receptor,FXR,Farnesoid X-activated receptor,Farnesol receptor HRR-1,Fxr,HRR-1,HRR1,NR1H4,Nr1h4,Nuclear receptor subfamily 1 group H member 4,PFIC5,RIP14,Retinoid X receptor-interacting protein 14 (RXR-interacting protein 14),Rxrip14
    Uniprot Accession Q3SZL0,Q60641,Q62735,Q96RI1
    Additional SwissProt Accessions: Q60641,Q3SZL0,Q62735,Q96RI1
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease
    Disease from KEGG Bile secretion
    Gene Ensembl ENSECAG00000018166, ENSMUSG00000047638, ENSBTAG00000013596, ENSCAFG00845006398, ENSMMUG00000003571, ENSG00000012504
    Target Classification Nuclear Receptors


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.