Explore CDK1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Target ID |
GM-T49898
|
Target Name |
CDK1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
983
|
Gene ID |
100072299 (Equus caballus), 100856079 (Canis lupus familiaris), 101101592 (Felis catus), 12534 (Mus musculus) 281061 (Bos taurus), 54237 (Rattus norvegicus), 699269 (Macaca mulatta), 983 (Homo sapiens)
|
Target Alternative Names |
CDK1,Cdk1,CDC2,Cdc2,Cdc2a,p34<CDC2>,CDC28A,P34CDC2
|
Uniprot Accession |
P11440,P48734,P39951,P06493
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Therapeutics Target
|
Disease |
cancer
|
Disease from KEGG |
p53 signaling pathway, Cellular senescence, Gap junction
|
Gene Ensembl |
ENSECAG00000009716, ENSCAFG00845002973, ENSMUSG00000019942, ENSBTAG00000010109, ENSMMUG00000019876, ENSG00000170312
|
Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CDK1 cDNA Clones/ORF Plasmid
CDK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo983 | Pre-made Human CDK1/CDC2/CDC28A siRNA oligo Duplex | 983 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo54237 | Pre-made Rat Cdk1/Cdc2/Cdc2a siRNA oligo Duplex | 54237 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo12534 | Pre-made Mouse Cdk1/Cdc2/Cdc2a siRNA oligo Duplex | 12534 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo699269 | Pre-made Cynomolgus/Rhesus macaque CDK1/CDC2 siRNA oligo Duplex | 699269 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101101592 | Pre-made Cat/Feline CDK1 siRNA oligo Duplex | 101101592 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo100856079 | Pre-made Dog/Canine CDK1/CDC2 siRNA oligo Duplex | 100856079 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo281061 | Pre-made Bovines/Cattle CDK1/CDC2 siRNA oligo Duplex | 281061 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100072299 | Pre-made Equine/Horse CDK1 siRNA oligo Duplex | 100072299 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CDK1 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T49898-Ab | Human | Anti-Human CDK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-rg-T49898-Ab | Rat | Anti-Rat CDK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-mg-T49898-Ab | Mouse | Anti-Mouse CDK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cynog-T49898-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CDK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-felg-T49898-Ab | Cat/Feline | Anti-Cat/Feline CDK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cang-T49898-Ab | Dog/Canine | Anti-Dog/Canine CDK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-bovg-T49898-Ab | Bovines/Cattle | Anti-Bovines/Cattle CDK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-equg-T49898-Ab | Equine/Horse | Anti-Equine/Horse CDK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CDK1 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T49898-Ag | Human | Human CDK1 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T49898-Ag | Rat | Rat CDK1 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T49898-Ag | Mouse | Mouse CDK1 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T49898-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CDK1 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T49898-Ag | Cat/Feline | Cat/Feline CDK1 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T49898-Ag | Dog/Canine | Dog/Canine CDK1 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T49898-Ag | Bovines/Cattle | Bovines/Cattle CDK1 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T49898-Ag | Equine/Horse | Equine/Horse CDK1 recombinant protein | Mammalian cell | Detail |