Recombinant multi-species CDK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
The Alternative Names of target: CDK1,Cyclin-dependent kinase 1,CDK1,Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase,CDC2,CDC28A,P34CDC2

Target products collectionGo to CDK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T49898-Ab-1/ GM-Tg-hg-T49898-Ab-2 Human CDK1 protein Human
GM-Tg-rg-T49898-Ab-1/ GM-Tg-rg-T49898-Ab-2 Rat CDK1 protein Rat
GM-Tg-mg-T49898-Ab-1/ GM-Tg-mg-T49898-Ab-2 Mouse CDK1 protein Mouse
GM-Tg-cynog-T49898-Ab-1/ GM-Tg-cynog-T49898-Ab-2 Cynomolgus/Rhesus macaque CDK1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T49898-Ab-1/ GM-Tg-felg-T49898-Ab-2 Feline CDK1 protein Feline
GM-Tg-cang-T49898-Ab-1/ GM-Tg-cang-T49898-Ab-2 Canine CDK1 protein Canine
GM-Tg-bovg-T49898-Ab-1/ GM-Tg-bovg-T49898-Ab-2 Bovine CDK1 protein Bovine
GM-Tg-equg-T49898-Ab-1/ GM-Tg-equg-T49898-Ab-2 Equine CDK1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T49898-Ab-1/ GM-Tg-hg-T49898-Ab-2; GM-Tg-rg-T49898-Ab-1/ GM-Tg-rg-T49898-Ab-2;
GM-Tg-mg-T49898-Ab-1/ GM-Tg-mg-T49898-Ab-2; GM-Tg-cynog-T49898-Ab-1/ GM-Tg-cynog-T49898-Ab-2;
GM-Tg-felg-T49898-Ab-1/ GM-Tg-felg-T49898-Ab-2; GM-Tg-cang-T49898-Ab-1/ GM-Tg-cang-T49898-Ab-2;
GM-Tg-bovg-T49898-Ab-1/ GM-Tg-bovg-T49898-Ab-2; GM-Tg-equg-T49898-Ab-1/ GM-Tg-equg-T49898-Ab-2
Products Name CDK1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CDK1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CDK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.