PTPN2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PTPN2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]

Target ID GM-T49156
Target Name PTPN2
Gene Group ldentifer
(Target Gene ID in Homo species)
5771
Gene ID 100057795 (Equus caballus), 101095923 (Felis catus), 114673846 (Macaca mulatta), 117063 (Rattus norvegicus)
19255 (Mus musculus), 490563 (Canis lupus familiaris), 540888 (Bos taurus), 5771 (Homo sapiens)
Target Alternative Names PTN2,PTPN2,PTPT,Ptpn2,Ptpt,T-cell protein-tyrosine phosphatase (TCPTP),TC-PTP,TC45,TC48,TCELLPTP,TCPTP,Tyrosine-protein phosphatase non-receptor type 2
Uniprot Accession P35233,Q06180,P17706
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease from KEGG JAK-STAT signaling pathway
Gene Ensembl ENSECAG00000000624, ENSMMUG00000055629, ENSMUSG00000024539, ENSCAFG00845005353, ENSBTAG00000010563, ENSG00000175354


Pre-made viral vector of PTPN2 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMPC000312Human PTPN2/PTN2/PTPT Mammalian (Non-Viral Vector) plasmidNM_002828.45771HumanMammalian (Non-Viral Vector) plasmidNull3xflag (C-Terminal)CMVDetail
pGMAD000060Mouse Ptpn2/AI325124/Ptpt Adenovirus plasmidNM_001127177.119255MouseAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMAD000060Mouse Ptpn2/AI325124/Ptpt Adenovirus particleNM_001127177.119255MouseAdenovirus particleGFP3xflag (C-Terminal)EF1Detail


PTPN2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo5771Pre-made Human PTPN2/PTN2/PTPT siRNA oligo Duplex5771HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo117063Pre-made Rat Ptpn2 siRNA oligo Duplex117063RatIn-vitro grade; in-vivo gradeDetail
pGMoligo19255Pre-made Mouse Ptpn2/Ptpt/TC-PTP siRNA oligo Duplex19255MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo114673846Pre-made Cynomolgus/Rhesus macaque PTPN2 siRNA oligo Duplex114673846Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101095923Pre-made Cat/Feline PTPN2 siRNA oligo Duplex101095923Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo490563Pre-made Dog/Canine PTPN2 siRNA oligo Duplex490563Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo540888Pre-made Bovines/Cattle PTPN2 siRNA oligo Duplex540888Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100057795Pre-made Equine/Horse PTPN2 siRNA oligo Duplex100057795Equine/HorseIn-vitro grade; in-vivo gradeDetail


PTPN2 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T49156-AbHumanAnti-Human PTPN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T49156-AbRatAnti-Rat PTPN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T49156-AbMouseAnti-Mouse PTPN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T49156-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque PTPN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T49156-AbCat/FelineAnti-Cat/Feline PTPN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T49156-AbDog/CanineAnti-Dog/Canine PTPN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T49156-AbBovines/CattleAnti-Bovines/Cattle PTPN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T49156-AbEquine/HorseAnti-Equine/Horse PTPN2 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


PTPN2 VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T49156-AgHumanHuman PTPN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T49156-AgRatRat PTPN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T49156-AgMouseMouse PTPN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T49156-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque PTPN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T49156-AgCat/FelineCat/Feline PTPN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T49156-AgDog/CanineDog/Canine PTPN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T49156-AgBovines/CattleBovines/Cattle PTPN2 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T49156-AgEquine/HorseEquine/Horse PTPN2 VLP (virus-like particle)HEK293Products Developing