EPCAM/CD326 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein
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Target
sublocation: Transmembrane Protein.
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
| Target ID | GM-T47863 |
| Target Name | EPCAM/CD326 |
|
Gene Group ldentifer （Target Gene ID in Homo species) |
4072 |
| Gene ID |
100053148 (Equus caballus), 101081794 (Felis catus), 17075 (Mus musculus), 171577 (Rattus norvegicus) 4072 (Homo sapiens), 481360 (Canis lupus familiaris), 514039 (Bos taurus), 677680 (Macaca mulatta) |
| Target Alternative Names | Adenocarcinoma-associated antigen,Ber-Ep4,BerEp4,CD326,Cell surface glycoprotein Trop-1,DIAR5,EGP,EGP-2,EGP314,EGP40,EPCAM,ESA,Egp314,Ep-CAM,EpCAM1,Epcam,Epithelial cell adhesion molecule,Epithelial cell surface antigen,Epithelial glycoprotein (EGP),Epithelial glycoprotein 314 (EGP314,GA733-2,HNPCC8,KS 1/4 antigen,KS1/4,KSA,LYNCH8,Ly74,M4S1,MIC18,MK-1,MOC-31,Major gastrointestinal tumor-associated protein GA733-2,TACSTD1,TROP1,Tacsd1,Tacstd1,Tumor-associated calcium signal transducer 1,gp40,hEGP314) |
| Uniprot Accession | Q99JW5,O55159,P16422,Q3T0L5,Q1WER1 |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target, INN Index |
| Disease | cancer, Ovary Cancer |
| Gene Ensembl | ENSECAG00000024630, ENSMUSG00000045394, ENSG00000119888, ENSCAFG00845005300, ENSBTAG00000006474, ENSMMUG00000012390 |
| Target Classification | Checkpoint-Immuno Oncology |
Pre-made viral vector of EPCAM/CD326 cDNA Clones/ORF Plasmid
| Cat No. | Product Name | NMID | GeneID | Species | Type | Marker | Fusion Tag | Promoter | Detail |
|---|---|---|---|---|---|---|---|---|---|
| pGMLV000293 | Human EPCAM/DIAR5/EGP-2 Lentivirus plasmid | NM_002354.2 | 4072 | Human | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMLV000875 | Human EPCAM/DIAR5/EGP-2 Lentivirus plasmid | NM_002354.2 | 4072 | Human | Lentivirus plasmid | Null | Null | CMV | Detail |
| pGMAAV000214 | Human EpCAM/DIAR5/EGP-2 Adeno-associate virus(AAV) plasmid | NM_002354 | 4072 | Human | Adeno-associate virus(AAV) plasmid | GFP | 3xflag (C-Terminal) | TBG | Detail |
| pGMAAV000236 | Human EPCAM/DIAR5/EGP-2 Adeno-associate virus(AAV) plasmid | NM_002354 | 4072 | Human | Adeno-associate virus(AAV) plasmid | GFP | Null | TBG | Detail |
| pGMAP000558 | Human EPCAM/CO-17A/CO17-1A Adenovirus plasmid | BC014785 | 4072 | Human | Adenovirus plasmid | GFP | 3xflag (C-Terminal) | EF1 | Detail |
| vGMLV000293 | Human EPCAM/DIAR5/EGP-2 Lentivirus particle | NM_002354.2 | 4072 | Human | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| vGMLV000875 | Human EPCAM/DIAR5/EGP-2 Lentivirus particle | NM_002354.2 | 4072 | Human | Lentivirus particle | Null | Null | CMV | Detail |
| vGMAAV000214 | Human EpCAM/DIAR5/EGP-2 Adeno-associate virus(AAV) particle | NM_002354 | 4072 | Human | Adeno-associate virus(AAV) particle | GFP | 3xflag (C-Terminal) | TBG | Detail |
| vGMAAV000236 | Human EPCAM/DIAR5/EGP-2 Adeno-associate virus(AAV) particle | NM_002354 | 4072 | Human | Adeno-associate virus(AAV) particle | GFP | Null | TBG | Detail |
| vGMAP000558 | Human EPCAM/CO-17A/CO17-1A Adenovirus particle | BC014785 | 4072 | Human | Adenovirus particle | GFP | 3xflag (C-Terminal) | EF1 | Detail |
| pGMLPm002282 | Mouse Epcam/CD326/EGP Lentivirus plasmid | NM_008532 | 17075 | Mouse | Lentivirus plasmid | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
| pGMPC004903 | Mouse Epcam/CD326/EGP Mammalian (Non-Viral Vector) plasmid | NM_008532.2 | 17075 | Mouse | Mammalian (Non-Viral Vector) plasmid | ZsGreen | Null | EF1 | Detail |
| vGMLPm002282 | Mouse Epcam/CD326/EGP Lentivirus particle | NM_008532 | 17075 | Mouse | Lentivirus particle | ZsGreen | 3xflag (C-Terminal) | CMV | Detail |
EPCAM/CD326 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|---|---|---|---|---|
| pGMoligo4072 | Pre-made Human EPCAM/ESA/KSA siRNA oligo Duplex | 4072 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171577 | Pre-made Rat Epcam/Egp314/Tacstd1 siRNA oligo Duplex | 171577 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17075 | Pre-made Mouse Epcam/EGP/Ly74 siRNA oligo Duplex | 17075 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo677680 | Pre-made Cynomolgus/Rhesus macaque EPCAM/Ep-CAM/TACSTD1 siRNA oligo Duplex | 677680 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081794 | Pre-made Cat/Feline EPCAM siRNA oligo Duplex | 101081794 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481360 | Pre-made Dog/Canine EPCAM/TACSTD1 siRNA oligo Duplex | 481360 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514039 | Pre-made Bovines/Cattle EPCAM/TACSTD1 siRNA oligo Duplex | 514039 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053148 | Pre-made Equine/Horse EPCAM siRNA oligo Duplex | 100053148 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EPCAM/CD326 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|---|---|---|---|---|
| GM-Tg-hg-T47863-Ab | Human | Anti-Human EPCAM/CD326 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T47863-Ab | Rat | Anti-Rat EPCAM/CD326 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T47863-Ab | Mouse | Anti-Mouse EPCAM/CD326 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T47863-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EPCAM/CD326 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T47863-Ab | Cat/Feline | Anti-Cat/Feline EPCAM/CD326 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T47863-Ab | Dog/Canine | Anti-Dog/Canine EPCAM/CD326 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T47863-Ab | Bovines/Cattle | Anti-Bovines/Cattle EPCAM/CD326 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T47863-Ab | Equine/Horse | Anti-Equine/Horse EPCAM/CD326 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EPCAM/CD326 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|---|---|---|---|
| GM-Tg-hg-T47863-Ag | Human | Human EPCAM/CD326 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T47863-Ag | Rat | Rat EPCAM/CD326 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T47863-Ag | Mouse | Mouse EPCAM/CD326 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T47863-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EPCAM/CD326 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T47863-Ag | Cat/Feline | Cat/Feline EPCAM/CD326 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T47863-Ag | Dog/Canine | Dog/Canine EPCAM/CD326 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T47863-Ag | Bovines/Cattle | Bovines/Cattle EPCAM/CD326 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T47863-Ag | Equine/Horse | Equine/Horse EPCAM/CD326 VLP (virus-like particle) | HEK293 | Products Developing |