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Human EPCAM/DIAR5/EGP-2 ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_002354)
Cat. No.: vGMAAV000236
Pre-made Human EPCAM/DIAR5/EGP-2 Adeno-associated virus particle for EPCAM in-vivo study, mechanism of action (MOA) research and EPCAM-associated gene therapy development.
At GM Vector Core (GMVC), we stand at the forefront of custom AAV development and produce distinct grades of AAVs employing state-of-the-art methodologies. Uncover more about our expertise.
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Product information
| Catalog No. | Product Name | AAV serotype | AAV Grade | AAV quantity |
| vGMAAV000236 | Human EPCAM Adeno-associate virus(AAV) particle | AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF | Pilot Grade | 1.0E+12VG/ml |
| 5.0E+12VG/ml | ||||
| 1E+13VG/ml | ||||
| 5E+13VG/ml | ||||
| 1E+14VG/ml | ||||
| Research Grade | 1.0E+12VG/ml | |||
| 5.0E+12VG/ml | ||||
| 1E+13VG/ml | ||||
| 5E+13VG/ml | ||||
| 1E+14VG/ml | ||||
| GMP-like Grade | inquiry | |||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAAV000236 |
| Gene Name | EPCAM |
| Accession Number | NM_002354 |
| Gene ID | 4072 |
| Species | Human |
| Product Type | Adeno-associate virus(AAV) particle (overexpression) |
| Insert Length | 945 bp |
| Gene Alias | DIAR5,EGP-2,EGP314,EGP40,ESA,HNPCC8,KS1/4,KSA,M4S1,MIC18,MK-1,TACSTD1,TROP1 |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | Null |
| Promoter | TBG |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGGCGCCCCCGCAGGTCCTCGCGTTCGGGCTTCTGCTTGCCGCGGCGACGGCGACTTTTGCCGCAGCTCAGGAAGAATGTGTCTGTGAAAACTACAAGCTGGCCGTAAACTGCTTTGTGAATAATAATCGTCAATGCCAGTGTACTTCAGTTGGTGCACAAAATACTGTCATTTGCTCAAAGCTGGCTGCCAAATGTTTGGTGATGAAGGCAGAAATGAATGGCTCAAAACTTGGGAGAAGAGCAAAACCTGAAGGGGCCCTCCAGAACAATGATGGGCTTTATGATCCTGACTGCGATGAGAGCGGGCTCTTTAAGGCCAAGCAGTGCAACGGCACCTCCATGTGCTGGTGTGTGAACACTGCTGGGGTCAGAAGAACAGACAAGGACACTGAAATAACCTGCTCTGAGCGAGTGAGAACCTACTGGATCATCATTGAACTAAAACACAAAGCAAGAGAAAAACCTTATGATAGTAAAAGTTTGCGGACTGCACTTCAGAAGGAGATCACAACGCGTTATCAACTGGATCCAAAATTTATCACGAGTATTTTGTATGAGAATAATGTTATCACTATTGATCTGGTTCAAAATTCTTCTCAAAAAACTCAGAATGATGTGGACATAGCTGATGTGGCTTATTATTTTGAAAAAGATGTTAAAGGTGAATCCTTGTTTCATTCTAAGAAAATGGACCTGACAGTAAATGGGGAACAACTGGATCTGGATCCTGGTCAAACTTTAATTTATTATGTTGATGAAAAAGCACCTGAATTCTCAATGCAGGGTCTAAAAGCTGGTGTTATTGCTGTTATTGTGGTTGTGGTGATAGCAGTTGTTGCTGGAATTGTTGTGCTGGTTATTTCCAGAAAGAAGAGAATGGCAAAGTATGAGAAGGCTGAGATAAAGGAGATGGGTGAGATGCATAGGGAACTCAATGCATAA |
| ORF Protein Sequence | MAPPQVLAFGLLLAAATATFAAAQEECVCENYKLAVNCFVNNNRQCQCTSVGAQNTVICSKLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDESGLFKAKQCNGTSMCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKAREKPYDSKSLRTALQKEITTRYQLDPKFITSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKKMDLTVNGEQLDLDPGQTLIYYVDEKAPEFSMQGLKAGVIAVIVVVVIAVVAGIVVLVISRKKRMAKYEKAEIKEMGEMHRELNA |
Reference
Data / case study
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Associated products
Target information
| Target ID | GM-T47863 |
| Target Name | EPCAM/CD326 |
|
Gene Group Identifier （Target Gene ID in Homo species) |
4072 |
| Gene ID |
100053148 (Equus caballus), 101081794 (Felis catus), 17075 (Mus musculus), 171577 (Rattus norvegicus) 4072 (Homo sapiens), 481360 (Canis lupus familiaris), 514039 (Bos taurus), 677680 (Macaca mulatta) |
| Gene Symbols & Synonyms | EPCAM,Epcam,EGP,Ly74,gp40,CD326,EGP-2,TROP1,Egp314,Ep-CAM,EpCAM1,Tacsd1,GA733-2,Tacstd1,ESA,KSA,M4S1,MK-1,DIAR5,EGP40,KS1/4,MIC18,BerEp4,EGP314,HNPCC8,LYNCH8,MOC-31,Ber-Ep4,TACSTD1 |
| Target Alternative Names | Adenocarcinoma-associated antigen,Ber-Ep4,BerEp4,CD326,Cell surface glycoprotein Trop-1,DIAR5,EGP,EGP-2,EGP314,EGP40,EPCAM,ESA,Egp314,Ep-CAM,EpCAM1,Epcam,Epithelial cell adhesion molecule,Epithelial cell surface antigen,Epithelial glycoprotein (EGP),Epithelial glycoprotein 314 (EGP314,GA733-2,HNPCC8,KS 1/4 antigen,KS1/4,KSA,LYNCH8,Ly74,M4S1,MIC18,MK-1,MOC-31,Major gastrointestinal tumor-associated protein GA733-2,TACSTD1,TROP1,Tacsd1,Tacstd1,Tumor-associated calcium signal transducer 1,gp40,hEGP314) |
| Uniprot Accession |
O55159,P16422,Q1WER1,Q3T0L5,Q99JW5
Additional SwissProt Accessions: Q99JW5,O55159,P16422,Q3T0L5,Q1WER1 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target, INN Index |
| Disease | cancer, Ovary Cancer |
| Disease from KEGG | |
| Gene Ensembl | ENSECAG00000024630, ENSMUSG00000045394, ENSG00000119888, ENSCAFG00845005300, ENSBTAG00000006474, ENSMMUG00000012390 |
| Target Classification | Checkpoint-Immuno Oncology |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.