Explore B23/NPM1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T45591
|
| Target Name |
B23/NPM1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4869
|
| Gene ID |
100059112 (Equus caballus), 101094904 (Felis catus), 18148 (Mus musculus), 25498 (Rattus norvegicus) 479292 (Canis lupus familiaris), 4869 (Homo sapiens), 614028 (Bos taurus), 706883 (Macaca mulatta)
|
| Target Alternative Names |
B23,B23NP,NO38,NPM,NPM1,Npm,Npm1,Nucleolar phosphoprotein B23,Nucleolar protein NO38,Nucleophosmin,Numatrin
|
| Uniprot Accession |
Q61937,P13084,P06748,Q3T160
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000021950, ENSMUSG00000057113, ENSCAFG00845001853, ENSG00000181163, ENSBTAG00000015316, ENSMMUG00000015781
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of B23/NPM1 cDNA Clones/ORF Plasmid
B23/NPM1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4869 | Pre-made Human NPM1/B23/NPM siRNA oligo Duplex | 4869 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25498 | Pre-made Rat Npm1/B23NP siRNA oligo Duplex | 25498 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18148 | Pre-made Mouse Npm1/B23/Npm siRNA oligo Duplex | 18148 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706883 | Pre-made Cynomolgus/Rhesus macaque NPM1 siRNA oligo Duplex | 706883 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094904 | Pre-made Cat/Feline NPM1 siRNA oligo Duplex | 101094904 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479292 | Pre-made Dog/Canine NPM1 siRNA oligo Duplex | 479292 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo614028 | Pre-made Bovines/Cattle NPM1 siRNA oligo Duplex | 614028 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059112 | Pre-made Equine/Horse NPM1 siRNA oligo Duplex | 100059112 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
B23/NPM1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T45591-Ab | Human | Anti-Human B23/NPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T45591-Ab | Rat | Anti-Rat B23/NPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T45591-Ab | Mouse | Anti-Mouse B23/NPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T45591-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque B23/NPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T45591-Ab | Cat/Feline | Anti-Cat/Feline B23/NPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T45591-Ab | Dog/Canine | Anti-Dog/Canine B23/NPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T45591-Ab | Bovines/Cattle | Anti-Bovines/Cattle B23/NPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T45591-Ab | Equine/Horse | Anti-Equine/Horse B23/NPM1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
B23/NPM1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T45591-Ag | Human | Human B23/NPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T45591-Ag | Rat | Rat B23/NPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T45591-Ag | Mouse | Mouse B23/NPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T45591-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque B23/NPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T45591-Ag | Cat/Feline | Cat/Feline B23/NPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T45591-Ag | Dog/Canine | Dog/Canine B23/NPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T45591-Ag | Bovines/Cattle | Bovines/Cattle B23/NPM1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T45591-Ag | Equine/Horse | Equine/Horse B23/NPM1 recombinant protein | Mammalian cell | Detail |