t-Plasminogen activator/tPA/PLAT Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore t-Plasminogen activator/tPA/PLAT gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Pre-made viral vector of t-Plasminogen activator/tPA/PLAT cDNA Clones/ORF Plasmid

t-Plasminogen activator/tPA/PLAT siRNA/miRNA/oligo for RNA interfence (RNAi)

t-Plasminogen activator/tPA/PLAT antibody/GMab

t-Plasminogen activator/tPA/PLAT recombinant protein