Explore TREM2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
| Target ID |
GM-T45086
|
| Target Name |
TREM2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
54209
|
| Gene ID |
100066180 (Equus caballus), 101099297 (Felis catus), 119863908 (Canis lupus familiaris), 301227 (Rattus norvegicus)
506467 (Bos taurus), 54209 (Homo sapiens), 719740 (Macaca mulatta), 83433 (Mus musculus)
|
| Target Alternative Names |
AD17,PLOSL2,TREM-2,TREM2,Trem2,Trem2-Mia,Trem2-Mib,Trem2a,Trem2b,Trem2c,Triggering receptor expressed on monocytes 2,Triggering receptor expressed on myeloid cells 2
|
| Uniprot Accession |
Q9NZC2,Q99NH8
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Osteoclast differentiation
|
| Gene Ensembl |
ENSCAFG00845014990, ENSBTAG00000007275, ENSG00000095970, ENSMMUG00000013920, ENSMUSG00000023992
|
Pre-made viral vector of TREM2 cDNA Clones/ORF Plasmid
TREM2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo54209 | Pre-made Human TREM2/AD17/PLOSL2 siRNA oligo Duplex | 54209 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo301227 | Pre-made Rat Trem2/Trem2-Mia/Trem2-Mib siRNA oligo Duplex | 301227 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83433 | Pre-made Mouse Trem2/TREM-2/Trem2a siRNA oligo Duplex | 83433 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719740 | Pre-made Cynomolgus/Rhesus macaque TREM2 siRNA oligo Duplex | 719740 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099297 | Pre-made Cat/Feline TREM2 siRNA oligo Duplex | 101099297 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119863908 | Pre-made Dog/Canine TREM2 siRNA oligo Duplex | 119863908 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506467 | Pre-made Bovines/Cattle TREM2 siRNA oligo Duplex | 506467 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066180 | Pre-made Equine/Horse TREM2 siRNA oligo Duplex | 100066180 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TREM2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T45086-Ab | Human | Anti-Human TREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T45086-Ab | Rat | Anti-Rat TREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T45086-Ab | Mouse | Anti-Mouse TREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T45086-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T45086-Ab | Cat/Feline | Anti-Cat/Feline TREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T45086-Ab | Dog/Canine | Anti-Dog/Canine TREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T45086-Ab | Bovines/Cattle | Anti-Bovines/Cattle TREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T45086-Ab | Equine/Horse | Anti-Equine/Horse TREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TREM2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T45086-Ag | Human | Human TREM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T45086-Ag | Rat | Rat TREM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T45086-Ag | Mouse | Mouse TREM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T45086-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TREM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T45086-Ag | Cat/Feline | Cat/Feline TREM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T45086-Ag | Dog/Canine | Dog/Canine TREM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T45086-Ag | Bovines/Cattle | Bovines/Cattle TREM2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T45086-Ag | Equine/Horse | Equine/Horse TREM2 VLP (virus-like particle) | HEK293 | Products Developing |
