Explore KCNB1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T44516
|
| Target Name |
KCNB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3745
|
| Gene ID |
100057009 (Equus caballus), 101101556 (Felis catus), 16500 (Mus musculus), 25736 (Rattus norvegicus)
3745 (Homo sapiens), 485918 (Canis lupus familiaris), 539528 (Bos taurus), 703520 (Macaca mulatta)
|
| Target Alternative Names |
DEE26,DRK1,DRK1PC,Delayed rectifier potassium channel 1 (DRK1,KCNB1,Kcnb1,Kcr1-1,Kv2.1,Potassium voltage-gated channel subfamily B member 1,Shab,Voltage-gated potassium channel subunit Kv2.1,h-DRK1)
|
| Uniprot Accession |
Q03717,P15387,Q14721
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000016080, ENSMUSG00000050556, ENSG00000158445, ENSCAFG00845024922, ENSBTAG00000027320, ENSMMUG00000006442
|
| Target Classification |
Ion Channel
|
Pre-made viral vector of KCNB1 cDNA Clones/ORF Plasmid
KCNB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3745 | Pre-made Human KCNB1/DRK1/DEE26 siRNA oligo Duplex | 3745 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25736 | Pre-made Rat Kcnb1/Shab/Kv2.1 siRNA oligo Duplex | 25736 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16500 | Pre-made Mouse Kcnb1/Shab/Kv2.1 siRNA oligo Duplex | 16500 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703520 | Pre-made Cynomolgus/Rhesus macaque KCNB1 siRNA oligo Duplex | 703520 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101556 | Pre-made Cat/Feline KCNB1 siRNA oligo Duplex | 101101556 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485918 | Pre-made Dog/Canine KCNB1 siRNA oligo Duplex | 485918 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539528 | Pre-made Bovines/Cattle KCNB1 siRNA oligo Duplex | 539528 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057009 | Pre-made Equine/Horse KCNB1 siRNA oligo Duplex | 100057009 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T44516-Ab | Human | Anti-Human KCNB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T44516-Ab | Rat | Anti-Rat KCNB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T44516-Ab | Mouse | Anti-Mouse KCNB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T44516-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T44516-Ab | Cat/Feline | Anti-Cat/Feline KCNB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T44516-Ab | Dog/Canine | Anti-Dog/Canine KCNB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T44516-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T44516-Ab | Equine/Horse | Anti-Equine/Horse KCNB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KCNB1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T44516-Ag | Human | Human KCNB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T44516-Ag | Rat | Rat KCNB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T44516-Ag | Mouse | Mouse KCNB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T44516-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T44516-Ag | Cat/Feline | Cat/Feline KCNB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T44516-Ag | Dog/Canine | Dog/Canine KCNB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T44516-Ag | Bovines/Cattle | Bovines/Cattle KCNB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T44516-Ag | Equine/Horse | Equine/Horse KCNB1 VLP (virus-like particle) | HEK293 | Products Developing |
