Human KCNB1/DEE26/DRK1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_004975)

Cat. No.: pGMPC000446
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human KCNB1/DEE26/DRK1 Non-Viral expression plasmid (overexpression vector) for mouse KCNB1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000446
Gene Name KCNB1
Accession Number NM_004975
Gene ID 3745
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 2577 bp
Gene Alias DEE26,DRK1,Kv2.1
Fluorescent Reporter mCherry
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCCGGCGGGCATGACGAAGCATGGCTCCCGCTCCACCAGCTCGCTGCCGCCCGAGCCCATGGAGATCGTGCGCAGCAAGGCGTGCTCTCGGCGGGTCCGCCTCAACGTCGGGGGGCTGGCGCACGAGGTACTCTGGCGTACCCTGGACCGCCTGCCCCGCACGCGGCTGGGCAAGCTCCGCGACTGCAACACGCACGACTCGCTGCTCGAGGTGTGCGATGACTACAGCCTCGACGACAACGAGTACTTCTTTGACCGCCACCCGGGCGCCTTCACCTCCATCCTCAACTTCTACCGCACTGGGCGACTGCACATGATGGAGGAGATGTGCGCGCTCAGCTTCAGCCAAGAGCTCGACTACTGGGGCATCGACGAGATCTACCTGGAGTCCTGCTGCCAGGCCCGCTACCACCAGAAGAAAGAGCAGATGAACGAGGAGCTCAAGCGTGAGGCCGAGACCCTACGGGAGCGGGAAGGCGAGGAGTTCGATAACACGTGCTGCGCAGAGAAGAGGAAAAAACTCTGGGACCTACTGGAGAAGCCCAATTCCTCTGTGGCTGCCAAGATCCTTGCCATAATTTCCATCATGTTCATCGTCCTCTCCACCATTGCCCTGTCCCTCAACACGCTGCCTGAGCTACAGAGCCTCGATGAGTTCGGCCAGTCCACAGACAACCCCCAGCTGGCCCACGTGGAGGCCGTGTGCATCGCATGGTTCACCATGGAGTACCTGCTGAGGTTCCTCTCCTCGCCCAAGAAGTGGAAGTTCTTCAAGGGCCCACTCAATGCCATTGACTTGTTGGCCATTCTGCCATACTATGTCACCATTTTCCTCACCGAATCCAACAAGAGCGTGCTGCAATTCCAGAATGTCCGCCGCGTGGTCCAGATCTTCCGCATCATGCGAATTCTCCGCATCCTTAAGCTTGCACGCCACTCCACTGGCCTCCAGTCTCTGGGCTTCACTTTGCGGAGGAGCTACAATGAGTTGGGCTTGCTCATCCTCTTCCTTGCCATGGGCATTATGATCTTCTCCAGCCTTGTCTTCTTTGCTGAGAAGGATGAGGACGACACCAAGTTCAAAAGCATCCCAGCCTCTTTCTGGTGGGCCACCATCACCATGACTACTGTTGGGTATGGAGACATCTACCCCAAGACTCTCCTGGGGAAAATTGTTGGGGGACTCTGCTGCATTGCAGGAGTCCTGGTGATTGCTCTTCCCATCCCCATCATCGTCAATAACTTCTCTGAGTTCTATAAGGAGCAGAAGAGACAGGAGAAAGCAATCAAACGGCGAGAGGCTCTGGAGAGAGCCAAGAGGAATGGCAGCATCGTATCCATGAACATGAAGGATGCTTTTGCCCGGAGCATTGAGATGATGGACATTGTGGTTGAGAAAAATGGGGAGAATATGGGTAAGAAAGACAAAGTACAAGATAACCACTTGTCTCCTAACAAATGGAAATGGACAAAGAGGACACTGTCTGAAACCAGCTCAAGTAAGTCCTTTGAAACCAAGGAACAGGGATCCCCTGAAAAAGCCAGATCGTCTTCTAGTCCTCAGCACCTGAACGTTCAGCAGTTGGAAGACATGTACAATAAGATGGCCAAGACCCAATCCCAACCCATCCTCAATACCAAGGAGTCAGCAGCACAGAGCAAACCAAAGGAAGAACTTGAAATGGAGAGTATCCCCAGCCCCGTAGCCCCTCTGCCCACTCGCACAGAAGGGGTCATTGACATGCGAAGTATGTCAAGCATTGATAGTTTCATTAGCTGTGCCACAGACTTCCCTGAGGCCACCAGATTCTCCCACAGCCCTTTGACATCACTCCCCAGCAAGACTGGGGGCAGCACAGCCCCAGAAGTGGGCTGGCGGGGAGCTCTGGGTGCCAGTGGTGGTAGGTTTGTGGAGGCCAACCCCAGCCCTGATGCCAGCCAGCACTCTAGTTTCTTCATCGAGAGCCCCAAGAGTTCCATGAAAACTAACAACCCTTTGAAGCTCCGAGCACTTAAAGTCAACTTCATGGAGGGTGACCCCAGTCCACTCCTCCCCGTTCTAGGGATGTACCATGACCCTCTCAGGAACCGGGGGAGTGCTGCGGCTGCTGTCGCTGGACTGGAGTGTGCCACGCTTTTGGACAAGGCTGTGCTGAGCCCAGAGTCCTCCATCTACACCACAGCAAGTGCTAAGACACCCCCCCGGTCTCCTGAGAAACACACAGCAATAGCGTTCAACTTTGAGGCGGGTGTCCACCAGTACATTGACGCAGACACAGATGATGAGGGACAGCTGCTCTACAGTGTGGACTCCAGCCCCCCCAAAAGCCTCCCTGGGAGCACCAGTCCGAAGTTCAGCACGGGGACAAGATCGGAGAAAAACCACTTTGAAAGCTCCCCTTTACCCACCTCCCCTAAGTTCTTAAGGCAGAACTGTATTTACTCCACAGAAGCATTGACTGGAAAAGGCCCCAGTGGTCAGGAAAAGTGCAAACTTGAGAACCACATCTCCCCTGACGTCCGTGTGTTGCCAGGGGGAGGAGCCCATGGAAGCACACGAGATCAGAGCATCTGA
ORF Protein Sequence MPAGMTKHGSRSTSSLPPEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWKFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNMKDAFARSIEMMDIVVEKNGENMGKKDKVQDNHLSPNKWKWTKRTLSETSSSKSFETKEQGSPEKARSSSSPQHLNVQQLEDMYNKMAKTQSQPILNTKESAAQSKPKEELEMESIPSPVAPLPTRTEGVIDMRSMSSIDSFISCATDFPEATRFSHSPLTSLPSKTGGSTAPEVGWRGALGASGGRFVEANPSPDASQHSSFFIESPKSSMKTNNPLKLRALKVNFMEGDPSPLLPVLGMYHDPLRNRGSAAAAVAGLECATLLDKAVLSPESSIYTTASAKTPPRSPEKHTAIAFNFEAGVHQYIDADTDDEGQLLYSVDSSPPKSLPGSTSPKFSTGTRSEKNHFESSPLPTSPKFLRQNCIYSTEALTGKGPSGQEKCKLENHISPDVRVLPGGGAHGSTRDQSI

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T44516-Ab Anti-KCNB1/ DRK1/ Kv2.1 monoclonal antibody
    Target Antigen GM-Tg-g-T44516-Ag KCNB1 VLP (virus-like particle)
    ORF Viral Vector pGMLP001673 Human KCNB1 Lentivirus plasmid
    ORF Viral Vector pGMPC000446 Human KCNB1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001673 Human KCNB1 Lentivirus particle


    Target information

    Target ID GM-T44516
    Target Name KCNB1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		3745
    Gene ID 100057009 (Equus caballus), 101101556 (Felis catus), 16500 (Mus musculus), 25736 (Rattus norvegicus)
    3745 (Homo sapiens), 485918 (Canis lupus familiaris), 539528 (Bos taurus), 703520 (Macaca mulatta)
    Gene Symbols & Synonyms KCNB1,Kcnb1,Shab,Kv2.1,Kcr1-1,DRK1PC,DRK1,DEE26
    Target Alternative Names DEE26,DRK1,DRK1PC,Delayed rectifier potassium channel 1 (DRK1,KCNB1,Kcnb1,Kcr1-1,Kv2.1,Potassium voltage-gated channel subfamily B member 1,Shab,Voltage-gated potassium channel subunit Kv2.1,h-DRK1)
    Uniprot Accession P15387,Q03717,Q14721
    Additional SwissProt Accessions: Q03717,P15387,Q14721
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease
    Disease from KEGG
    Gene Ensembl ENSECAG00000016080, ENSMUSG00000050556, ENSG00000158445, ENSCAFG00845024922, ENSBTAG00000027320, ENSMMUG00000006442
    Target Classification Ion Channel


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.