Explore Connexin 43/GJA1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]
| Target ID |
GM-T44479
|
| Target Name |
Connexin 43/GJA1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2697
|
| Gene ID |
100067229 (Equus caballus), 101100211 (Felis catus), 14609 (Mus musculus), 24392 (Rattus norvegicus)
2697 (Homo sapiens), 281193 (Bos taurus), 403418 (Canis lupus familiaris), 714344 (Macaca mulatta)
|
| Target Alternative Names |
AVSD3,CMDR,CX43,CXNK1,Cnx43,Connexin 43,Connexin-43 (Cx43),Cx43,Cx43alpha1,Cxnk1,EKVP,EKVP3,GJA1,GJAL,Gap junction 43 kDa heart protein,Gap junction alpha-1 protein,Gja-1,Gja1,HLHS1,HSS,Npm1,ODDD,PPKCA,connexin43,cx43
|
| Uniprot Accession |
P23242,P08050,P17302,P18246,Q6S9C0
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Gap junction, Arrhythmogenic right ventricular cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000005525, ENSMUSG00000050953, ENSG00000152661, ENSBTAG00000001835, ENSCAFG00845009132, ENSMMUG00000005225
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of Connexin 43/GJA1 cDNA Clones/ORF Plasmid
Connexin 43/GJA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2697 | Pre-made Human GJA1/HSS/CMDR siRNA oligo Duplex | 2697 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24392 | Pre-made Rat Gja1/Cx43/Cxnk1 siRNA oligo Duplex | 24392 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14609 | Pre-made Mouse Gja1/Cx43/Npm1 siRNA oligo Duplex | 14609 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714344 | Pre-made Cynomolgus/Rhesus macaque GJA1 siRNA oligo Duplex | 714344 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100211 | Pre-made Cat/Feline GJA1 siRNA oligo Duplex | 101100211 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403418 | Pre-made Dog/Canine GJA1/cx43 siRNA oligo Duplex | 403418 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281193 | Pre-made Bovines/Cattle GJA1/CXNK1 siRNA oligo Duplex | 281193 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067229 | Pre-made Equine/Horse GJA1/CX43/CXNK1 siRNA oligo Duplex | 100067229 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Connexin 43/GJA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T44479-Ab | Human | Anti-Human Connexin 43/GJA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T44479-Ab | Rat | Anti-Rat Connexin 43/GJA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T44479-Ab | Mouse | Anti-Mouse Connexin 43/GJA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T44479-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Connexin 43/GJA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T44479-Ab | Cat/Feline | Anti-Cat/Feline Connexin 43/GJA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T44479-Ab | Dog/Canine | Anti-Dog/Canine Connexin 43/GJA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T44479-Ab | Bovines/Cattle | Anti-Bovines/Cattle Connexin 43/GJA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T44479-Ab | Equine/Horse | Anti-Equine/Horse Connexin 43/GJA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Connexin 43/GJA1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T44479-Ag | Human | Human Connexin 43/GJA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T44479-Ag | Rat | Rat Connexin 43/GJA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T44479-Ag | Mouse | Mouse Connexin 43/GJA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T44479-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Connexin 43/GJA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T44479-Ag | Cat/Feline | Cat/Feline Connexin 43/GJA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T44479-Ag | Dog/Canine | Dog/Canine Connexin 43/GJA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T44479-Ag | Bovines/Cattle | Bovines/Cattle Connexin 43/GJA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T44479-Ag | Equine/Horse | Equine/Horse Connexin 43/GJA1 VLP (virus-like particle) | HEK293 | Products Developing |
