Explore RPS6KB2/S6K2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015]
| Target ID |
GM-T42760
|
| Target Name |
RPS6KB2/S6K2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6199
|
| Gene ID |
100053005 (Equus caballus), 101091812 (Felis catus), 361696 (Rattus norvegicus), 506083 (Bos taurus)
58988 (Mus musculus), 610499 (Canis lupus familiaris), 6199 (Homo sapiens), 721731 (Macaca mulatta)
|
| Target Alternative Names |
70 kDa ribosomal protein S6 kinase 2 (P70S6K2,KLS,P70-beta,P70-beta-1,P70-beta-2,RPS6KB2,Ribosomal protein S6 kinase beta-2,Rps6kb2,S6 kinase-related kinase (SRK),S6K-beta-2,S6K-beta2,S6K2,S6KB,S6KI(2),S6Kbeta,SRK,STK14B,Serine/threonine-protein kinase 14B,p70 S6 kinase beta,p70 S6K-beta,p70 S6KB,p70 ribosomal S6 kinase beta (S6K-beta,p70(S6K)-beta,p70-S6K 2),p70-beta),p70S6Kb
|
| Uniprot Accession |
Q9Z1M4,Q9UBS0
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, TGF-beta signaling pathway, Insulin resistance, Human cytomegalovirus infection, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer
|
| Gene Ensembl |
ENSECAG00000012221, ENSBTAG00000009175, ENSMUSG00000024830, ENSCAFG00845010235, ENSG00000175634, ENSMMUG00000005483
|
Pre-made viral vector of RPS6KB2/S6K2 cDNA Clones/ORF Plasmid
RPS6KB2/S6K2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6199 | Pre-made Human RPS6KB2/KLS/SRK siRNA oligo Duplex | 6199 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361696 | Pre-made Rat Rps6kb2 siRNA oligo Duplex | 361696 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58988 | Pre-made Mouse Rps6kb2/S6K2/S6K-beta-2 siRNA oligo Duplex | 58988 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721731 | Pre-made Cynomolgus/Rhesus macaque RPS6KB2 siRNA oligo Duplex | 721731 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091812 | Pre-made Cat/Feline RPS6KB2 siRNA oligo Duplex | 101091812 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610499 | Pre-made Dog/Canine RPS6KB2 siRNA oligo Duplex | 610499 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506083 | Pre-made Bovines/Cattle RPS6KB2 siRNA oligo Duplex | 506083 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053005 | Pre-made Equine/Horse RPS6KB2 siRNA oligo Duplex | 100053005 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RPS6KB2/S6K2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T42760-Ab | Human | Anti-Human RPS6KB2/S6K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T42760-Ab | Rat | Anti-Rat RPS6KB2/S6K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T42760-Ab | Mouse | Anti-Mouse RPS6KB2/S6K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T42760-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RPS6KB2/S6K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T42760-Ab | Cat/Feline | Anti-Cat/Feline RPS6KB2/S6K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T42760-Ab | Dog/Canine | Anti-Dog/Canine RPS6KB2/S6K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T42760-Ab | Bovines/Cattle | Anti-Bovines/Cattle RPS6KB2/S6K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T42760-Ab | Equine/Horse | Anti-Equine/Horse RPS6KB2/S6K2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RPS6KB2/S6K2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T42760-Ag | Human | Human RPS6KB2/S6K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T42760-Ag | Rat | Rat RPS6KB2/S6K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T42760-Ag | Mouse | Mouse RPS6KB2/S6K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T42760-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RPS6KB2/S6K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T42760-Ag | Cat/Feline | Cat/Feline RPS6KB2/S6K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T42760-Ag | Dog/Canine | Dog/Canine RPS6KB2/S6K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T42760-Ag | Bovines/Cattle | Bovines/Cattle RPS6KB2/S6K2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T42760-Ag | Equine/Horse | Equine/Horse RPS6KB2/S6K2 recombinant protein | Mammalian cell | Detail |
