Human RPS6KB2/KLS/p70(S6K)-beta ORF/cDNA clone-Lentivirus plasmid (NM_003952.2)

Cat. No.: pGMLP005493
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human RPS6KB2/KLS/p70(S6K)-beta Lentiviral expression plasmid for RPS6KB2 lentivirus packaging, RPS6KB2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP005493
Gene Name RPS6KB2
Accession Number NM_003952.2
Gene ID 6199
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1449 bp
Gene Alias KLS,p70(S6K)-beta,P70-beta,P70-beta-1,P70-beta-2,p70S6Kb,S6K-beta2,S6K2,S6KB,S6Kbeta,S6KI(2),SRK,STK14B
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCGGCCGTGTTTGATTTGGATTTGGAGACGGAGGAAGGCAGCGAGGGCGAGGGCGAGCCAGAGCTCAGCCCCGCGGACGCATGTCCCCTTGCCGAGTTGAGGGCAGCTGGCCTAGAGCCTGTGGGACACTATGAAGAGGTGGAGCTGACTGAGACCAGCGTGAACGTTGGCCCAGAGCGCATCGGGCCCCACTGCTTTGAGCTGCTGCGTGTGCTGGGCAAGGGGGGCTATGGCAAGGTGTTCCAGGTGCGAAAGGTGCAAGGCACCAACTTGGGCAAAATATATGCCATGAAAGTCCTAAGGAAGGCCAAAATTGTGCGCAATGCCAAGGACACAGCACACACACGGGCTGAGCGGAACATTCTAGAGTCAGTGAAGCACCCCTTTATTGTGGAACTGGCCTATGCCTTCCAGACTGGTGGCAAACTCTACCTCATCCTTGAGTGCCTCAGTGGTGGCGAGCTCTTCACGCATCTGGAGCGAGAGGGCATCTTCCTGGAAGATACGGCCTGCTTCTACCTGGCTGAGATCACGCTGGCCCTGGGCCATCTCCACTCCCAGGGCATCATCTACCGGGACCTCAAGCCCGAGAACATCATGCTCAGCAGCCAGGGCCACATCAAACTGACCGACTTTGGACTCTGCAAGGAGTCTATCCATGAGGGCGCCGTCACTCACACCTTCTGCGGCACCATTGAGTACATGGCCCCTGAGATTCTGGTGCGCAGTGGCCACAACCGGGCTGTGGACTGGTGGAGCCTGGGGGCCCTGATGTACGACATGCTCACTGGATCGCCGCCCTTCACCGCAGAGAACCGGAAGAAAACCATGGATAAGATCATCAGGGGCAAGCTGGCACTGCCCCCCTACCTCACCCCAGATGCCCGGGACCTTGTCAAAAAGTTTCTGAAACGGAATCCCAGCCAGCGGATTGGGGGTGGCCCAGGGGATGCTGCTGATGTGCAGAGACATCCCTTTTTCCGGCACATGAATTGGGACGACCTTCTGGCCTGGCGTGTGGACCCCCCTTTCAGGCCCTGTCTGCAGTCAGAGGAGGACGTGAGCCAGTTTGATACCCGCTTCACACGGCAGACGCCGGTGGACAGTCCTGATGACACAGCCCTCAGCGAGAGTGCCAACCAGGCCTTCCTGGGCTTCACATACGTGGCGCCGTCTGTCCTGGACAGCATCAAGGAGGGCTTCTCCTTCCAGCCCAAGCTGCGCTCACCCAGGCGCCTCAACAGTAGCCCCCGGGCCCCCGTCAGCCCCCTCAAGTTCTCCCCTTTTGAGGGGTTTCGGCCCAGCCCCAGCCTGCCGGAGCCCACGGAGCTACCTCTACCTCCACTCCTGCCACCGCCGCCGCCCTCGACCACCGCCCCTCTCCCCATCCGTCCCCCCTCAGGGACCAAGAAGTCCAAGAGGGGCCGTGGGCGTCCAGGGCGCTAG
ORF Protein Sequence MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRPGR

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T42760-Ab Anti-RPS6KB2 monoclonal antibody
    Target Antigen GM-Tg-g-T42760-Ag RPS6KB2 protein
    ORF Viral Vector pGMLP005493 Human RPS6KB2 Lentivirus plasmid
    ORF Viral Vector pGMLP005707 Human RPS6KB2 Lentivirus plasmid
    ORF Viral Vector vGMLP005493 Human RPS6KB2 Lentivirus particle
    ORF Viral Vector vGMLP005707 Human RPS6KB2 Lentivirus particle


    Target information

    Target ID GM-T42760
    Target Name RPS6KB2/S6K2
    Gene Group Identifier
    （Target Gene ID in Homo species)         		6199
    Gene ID 100053005 (Equus caballus), 101091812 (Felis catus), 361696 (Rattus norvegicus), 506083 (Bos taurus)
    58988 (Mus musculus), 610499 (Canis lupus familiaris), 6199 (Homo sapiens), 721731 (Macaca mulatta)
    Gene Symbols & Synonyms RPS6KB2,Rps6kb2,S6K2,S6K-beta-2,KLS,SRK,S6KB,STK14B,S6KI(2),S6Kbeta,p70S6Kb,P70-beta,S6K-beta2,P70-beta-1,P70-beta-2,p70(S6K)-beta
    Target Alternative Names 70 kDa ribosomal protein S6 kinase 2 (P70S6K2,KLS,P70-beta,P70-beta-1,P70-beta-2,RPS6KB2,Ribosomal protein S6 kinase beta-2,Rps6kb2,S6 kinase-related kinase (SRK),S6K-beta-2,S6K-beta2,S6K2,S6KB,S6KI(2),S6Kbeta,SRK,STK14B,Serine/threonine-protein kinase 14B,p70 S6 kinase beta,p70 S6K-beta,p70 S6KB,p70 ribosomal S6 kinase beta (S6K-beta,p70(S6K)-beta,p70-S6K 2),p70-beta),p70S6Kb
    Uniprot Accession Q9UBS0,Q9Z1M4
    Additional SwissProt Accessions: Q9Z1M4,Q9UBS0
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease
    Disease from KEGG EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, TGF-beta signaling pathway, Insulin resistance, Human cytomegalovirus infection, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer
    Gene Ensembl ENSECAG00000012221, ENSBTAG00000009175, ENSMUSG00000024830, ENSCAFG00845010235, ENSG00000175634, ENSMMUG00000005483
    Target Classification


    About GMVC

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