Explore GLI1/Gli1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
| Target ID |
GM-T40890
|
| Target Name |
GLI1/Gli1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2735
|
| Gene ID |
100033937 (Equus caballus), 101092697 (Felis catus), 140589 (Rattus norvegicus), 14632 (Mus musculus) 2735 (Homo sapiens), 481126 (Canis lupus familiaris), 517588 (Bos taurus), 714843 (Macaca mulatta)
|
| Target Alternative Names |
GLI,GLI1,Gli,Gli1,Glioma-associated oncogene,Oncogene GLI,PAPA8,PPD1,Zfp-5,Zfp5,Zinc finger protein GLI1
|
| Uniprot Accession |
P47806,P08151
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
cAMP signaling pathway, Pathways in cancer, Basal cell carcinoma
|
| Gene Ensembl |
ENSECAG00000011246, ENSMUSG00000025407, ENSG00000111087, ENSCAFG00845011836, ENSBTAG00000006631, ENSMMUG00000022058
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of GLI1/Gli1 cDNA Clones/ORF Plasmid
GLI1/Gli1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2735 | Pre-made Human GLI1/GLI/PPD1 siRNA oligo Duplex | 2735 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo140589 | Pre-made Rat Gli1/Gli siRNA oligo Duplex | 140589 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14632 | Pre-made Mouse Gli1/Zfp5/Zfp-5 siRNA oligo Duplex | 14632 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714843 | Pre-made Cynomolgus/Rhesus macaque GLI1 siRNA oligo Duplex | 714843 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092697 | Pre-made Cat/Feline GLI1 siRNA oligo Duplex | 101092697 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481126 | Pre-made Dog/Canine GLI1 siRNA oligo Duplex | 481126 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo517588 | Pre-made Bovines/Cattle GLI1/GLI siRNA oligo Duplex | 517588 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033937 | Pre-made Equine/Horse GLI1 siRNA oligo Duplex | 100033937 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GLI1/Gli1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T40890-Ab | Human | Anti-Human GLI1/Gli1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T40890-Ab | Rat | Anti-Rat GLI1/Gli1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T40890-Ab | Mouse | Anti-Mouse GLI1/Gli1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T40890-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GLI1/Gli1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T40890-Ab | Cat/Feline | Anti-Cat/Feline GLI1/Gli1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T40890-Ab | Dog/Canine | Anti-Dog/Canine GLI1/Gli1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T40890-Ab | Bovines/Cattle | Anti-Bovines/Cattle GLI1/Gli1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T40890-Ab | Equine/Horse | Anti-Equine/Horse GLI1/Gli1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GLI1/Gli1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T40890-Ag | Human | Human GLI1/Gli1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T40890-Ag | Rat | Rat GLI1/Gli1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T40890-Ag | Mouse | Mouse GLI1/Gli1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T40890-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GLI1/Gli1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T40890-Ag | Cat/Feline | Cat/Feline GLI1/Gli1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T40890-Ag | Dog/Canine | Dog/Canine GLI1/Gli1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T40890-Ag | Bovines/Cattle | Bovines/Cattle GLI1/Gli1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T40890-Ag | Equine/Horse | Equine/Horse GLI1/Gli1 recombinant protein | Mammalian cell | Detail |