Glucocorticoid receptor/NR3C1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Glucocorticoid receptor/NR3C1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]

Pre-made viral vector of Glucocorticoid receptor/NR3C1 cDNA Clones/ORF Plasmid

Glucocorticoid receptor/NR3C1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Glucocorticoid receptor/NR3C1 antibody/GMab

Glucocorticoid receptor/NR3C1 recombinant protein