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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T39977
|
| Target Name |
MIF
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4282
|
| Gene ID |
100053618 (Equus caballus), 101090298 (Felis catus), 17319 (Mus musculus), 280858 (Bos taurus)
4282 (Homo sapiens), 574298 (Macaca mulatta), 595146 (Canis lupus familiaris), 81683 (Rattus norvegicus)
|
| Target Alternative Names |
DER6,GIF,GLIF,Glif,Glycosylation-inhibiting factor (GIF),L-dopachrome isomerase,L-dopachrome tautomerase,MIF,MMIF,Macrophage migration inhibitory factor,Mif,Phenylpyruvate tautomerase
|
| Uniprot Accession |
P34884,P80177,P14174,Q6DN04,P30904
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer, Ovary Cancer, Kidney transplant rejection, Congenital occlusion of ureteropelvic junction, Sepsis
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSMUSG00000033307, ENSBTAG00000007375, ENSG00000240972, ENSMMUG00000009106, ENSCAFG00845024852
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of MIF cDNA Clones/ORF Plasmid
MIF siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4282 | Pre-made Human MIF/GIF/GLIF siRNA oligo Duplex | 4282 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81683 | Pre-made Rat Mif siRNA oligo Duplex | 81683 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17319 | Pre-made Mouse Mif/GIF/DER6 siRNA oligo Duplex | 17319 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574298 | Pre-made Cynomolgus/Rhesus macaque MIF siRNA oligo Duplex | 574298 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090298 | Pre-made Cat/Feline MIF siRNA oligo Duplex | 101090298 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo595146 | Pre-made Dog/Canine MIF siRNA oligo Duplex | 595146 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280858 | Pre-made Bovines/Cattle MIF siRNA oligo Duplex | 280858 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053618 | Pre-made Equine/Horse MIF/MMIF siRNA oligo Duplex | 100053618 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MIF antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T39977-Ab | Human | Anti-Human MIF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T39977-Ab | Rat | Anti-Rat MIF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T39977-Ab | Mouse | Anti-Mouse MIF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T39977-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MIF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T39977-Ab | Cat/Feline | Anti-Cat/Feline MIF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T39977-Ab | Dog/Canine | Anti-Dog/Canine MIF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T39977-Ab | Bovines/Cattle | Anti-Bovines/Cattle MIF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T39977-Ab | Equine/Horse | Anti-Equine/Horse MIF monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MIF VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T39977-Ag | Human | Human MIF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T39977-Ag | Rat | Rat MIF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T39977-Ag | Mouse | Mouse MIF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T39977-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MIF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T39977-Ag | Cat/Feline | Cat/Feline MIF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T39977-Ag | Dog/Canine | Dog/Canine MIF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T39977-Ag | Bovines/Cattle | Bovines/Cattle MIF VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T39977-Ag | Equine/Horse | Equine/Horse MIF VLP (virus-like particle) | HEK293 | Products Developing |
