Explore LAIR1/CD305 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
| Target ID |
GM-T39047
|
| Target Name |
LAIR1/CD305
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3903
|
| Gene ID |
101081847 (Felis catus), 3903 (Homo sapiens), 484308 (Canis lupus familiaris), 615295 (Bos taurus)
|
| Target Alternative Names |
CD305,LAIR-1,LAIR1,Leukocyte-associated immunoglobulin-like receptor 1,hLAIR1
|
| Uniprot Accession |
Q6GTX8
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Pregnant state
|
| Gene Ensembl |
ENSG00000167613, ENSCAFG00845002261, ENSBTAG00000026080
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of LAIR1/CD305 cDNA Clones/ORF Plasmid
LAIR1/CD305 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3903 | Pre-made Human LAIR1/CD305/LAIR-1 siRNA oligo Duplex | 3903 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081847 | Pre-made Cat/Feline LAIR1 siRNA oligo Duplex | 101081847 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484308 | Pre-made Dog/Canine LAIR1 siRNA oligo Duplex | 484308 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615295 | Pre-made Bovines/Cattle LAIR1 siRNA oligo Duplex | 615295 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
LAIR1/CD305 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T39047-Ab | Human | Anti-Human LAIR1/CD305 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T39047-Ab | Cat/Feline | Anti-Cat/Feline LAIR1/CD305 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T39047-Ab | Dog/Canine | Anti-Dog/Canine LAIR1/CD305 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T39047-Ab | Bovines/Cattle | Anti-Bovines/Cattle LAIR1/CD305 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LAIR1/CD305 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T39047-Ag | Human | Human LAIR1/CD305 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T39047-Ag | Cat/Feline | Cat/Feline LAIR1/CD305 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T39047-Ag | Dog/Canine | Dog/Canine LAIR1/CD305 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T39047-Ag | Bovines/Cattle | Bovines/Cattle LAIR1/CD305 VLP (virus-like particle) | HEK293 | Products Developing |
