ASGR1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore ASGR1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Target ID	GM-T32780
Target Name	ASGR1
Gene Group ldentifer （Target Gene ID in Homo species)	432
Gene ID	432 (Homo sapiens), 721786 (Macaca mulatta)
Target Alternative Names	ASGP-R 1,ASGPR,ASGPR 1,ASGPR1,ASGR1,Asialoglycoprotein receptor 1,C-type lectin domain family 4 member H1,CLEC4H1,HL-1,Hepatic lectin H1 (HL-1)
Uniprot Accession	P07306
Protein Sub-location	Transmembrane Protein
Category	Therapeutics Target
Disease from KEGG	Thyroid hormone synthesis
Gene Ensembl	ENSG00000141505, ENSMMUG00000003247

Pre-made viral vector of ASGR1 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP002034	Human ASGR1/ASGPR/ASGPR1 Lentivirus plasmid	NM_001671	432	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV002104	Human ASGR1/ASGPR/ASGPR1 Lentivirus plasmid	NM_001671.5	432	Human	Lentivirus plasmid	ZsGreen	Null	CMV	Detail
vGMLP002034	Human ASGR1/ASGPR/ASGPR1 Lentivirus particle	NM_001671	432	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV002104	Human ASGR1/ASGPR/ASGPR1 Lentivirus particle	NM_001671.5	432	Human	Lentivirus particle	ZsGreen	Null	CMV	Detail

ASGR1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo432	Pre-made Human ASGR1/HL-1/ASGPR siRNA oligo Duplex	432	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo721786	Pre-made Cynomolgus/Rhesus macaque ASGR1 siRNA oligo Duplex	721786	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail

ASGR1 antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T32780-Ab	Human	Anti-Human ASGR1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail
GM-Tg-cynog-T32780-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque ASGR1 monoclonal antibody	mab	FACS/Biofunctional Antibody, Therapeutics Target antibody	Detail

ASGR1 VLP (virus-like particle)/protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T32780-Ag	Human	Human ASGR1 VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-cynog-T32780-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque ASGR1 VLP (virus-like particle)	HEK293	Products Developing