Explore CXCL10/IP-10 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020]
| Target ID |
GM-T30635
|
| Target Name |
CXCL10/IP-10
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3627
|
| Gene ID |
100050993 (Equus caballus), 101100131 (Felis catus), 245920 (Rattus norvegicus), 3627 (Homo sapiens)
478432 (Canis lupus familiaris), 574243 (Macaca mulatta), 615107 (Bos taurus)
|
| Target Alternative Names |
CXCL10,Cxcl10,IP-10,Scyb10,C7,IFI10,INP10,crg-2,mob-1,SCYB10,gIP-10
|
| Uniprot Accession |
P48973,P02778,Q5KSV9,Q8MIZ1,Q2KIQ8
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index, Cytokine Target
|
| Disease |
cancer, Breast Cancer, Complications of kidney transplant, Bacterial sepsis of newborn, Acute kidney failure
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Hepatitis C, Influenza A, Epstein-Barr virus infection
|
| Gene Ensembl |
ENSG00000169245, ENSCAFG00845029862, ENSMMUG00000020903, ENSBTAG00000001725
|
| Target Classification |
|
Pre-made viral vector of CXCL10/IP-10 cDNA Clones/ORF Plasmid
CXCL10/IP-10 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3627 | Pre-made Human CXCL10/C7/IFI10 siRNA oligo Duplex | 3627 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo245920 | Pre-made Rat Cxcl10/IP-10/Scyb10 siRNA oligo Duplex | 245920 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574243 | Pre-made Cynomolgus/Rhesus macaque CXCL10 siRNA oligo Duplex | 574243 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100131 | Pre-made Cat/Feline CXCL10 siRNA oligo Duplex | 101100131 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478432 | Pre-made Dog/Canine CXCL10 siRNA oligo Duplex | 478432 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615107 | Pre-made Bovines/Cattle CXCL10 siRNA oligo Duplex | 615107 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050993 | Pre-made Equine/Horse CXCL10 siRNA oligo Duplex | 100050993 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CXCL10/IP-10 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T30635-Ab | Human | Anti-Human CXCL10/IP-10 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T30635-Ab | Rat | Anti-Rat CXCL10/IP-10 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T30635-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CXCL10/IP-10 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T30635-Ab | Cat/Feline | Anti-Cat/Feline CXCL10/IP-10 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T30635-Ab | Dog/Canine | Anti-Dog/Canine CXCL10/IP-10 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T30635-Ab | Bovines/Cattle | Anti-Bovines/Cattle CXCL10/IP-10 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T30635-Ab | Equine/Horse | Anti-Equine/Horse CXCL10/IP-10 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
CXCL10/IP-10 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T30635-Ag | Human | Human CXCL10/IP-10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T30635-Ag | Rat | Rat CXCL10/IP-10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T30635-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CXCL10/IP-10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T30635-Ag | Cat/Feline | Cat/Feline CXCL10/IP-10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T30635-Ag | Dog/Canine | Dog/Canine CXCL10/IP-10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T30635-Ag | Bovines/Cattle | Bovines/Cattle CXCL10/IP-10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T30635-Ag | Equine/Horse | Equine/Horse CXCL10/IP-10 recombinant protein | Mammalian cell | Detail |
