Explore Iduronate 2 sulfatase/IDS gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
| Target ID |
GM-T28993
|
| Target Name |
Iduronate 2 sulfatase/IDS
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3423
|
| Gene ID |
101081450 (Felis catus), 111771607 (Equus caballus), 15931 (Mus musculus), 3423 (Homo sapiens)
363513 (Rattus norvegicus), 492194 (Canis lupus familiaris), 541272 (Bos taurus), 700892 (Macaca mulatta)
|
| Target Alternative Names |
Alpha-L-iduronate sulfate sulfatase (Idursulfase),ID2S,IDS,Ids,Iduronate 2 sulfatase,Iduronate 2-sulfatase,MPS2,SIDS
|
| Uniprot Accession |
Q08890,P22304
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Lysosome, Glycosaminoglycan degradation
|
| Gene Ensembl |
ENSECAG00000033355, ENSMUSG00000035847, ENSG00000010404, ENSCAFG00845021782, ENSBTAG00000011056, ENSMMUG00000000671
|
Pre-made viral vector of Iduronate 2 sulfatase/IDS cDNA Clones/ORF Plasmid
Iduronate 2 sulfatase/IDS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3423 | Pre-made Human IDS/ID2S/MPS2 siRNA oligo Duplex | 3423 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363513 | Pre-made Rat Ids siRNA oligo Duplex | 363513 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15931 | Pre-made Mouse Ids siRNA oligo Duplex | 15931 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700892 | Pre-made Cynomolgus/Rhesus macaque IDS siRNA oligo Duplex | 700892 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081450 | Pre-made Cat/Feline IDS siRNA oligo Duplex | 101081450 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo492194 | Pre-made Dog/Canine IDS siRNA oligo Duplex | 492194 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo541272 | Pre-made Bovines/Cattle IDS siRNA oligo Duplex | 541272 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111771607 | Pre-made Equine/Horse IDS siRNA oligo Duplex | 111771607 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Iduronate 2 sulfatase/IDS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T28993-Ab | Human | Anti-Human Iduronate 2 sulfatase/IDS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T28993-Ab | Rat | Anti-Rat Iduronate 2 sulfatase/IDS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T28993-Ab | Mouse | Anti-Mouse Iduronate 2 sulfatase/IDS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T28993-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Iduronate 2 sulfatase/IDS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T28993-Ab | Cat/Feline | Anti-Cat/Feline Iduronate 2 sulfatase/IDS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T28993-Ab | Dog/Canine | Anti-Dog/Canine Iduronate 2 sulfatase/IDS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T28993-Ab | Bovines/Cattle | Anti-Bovines/Cattle Iduronate 2 sulfatase/IDS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T28993-Ab | Equine/Horse | Anti-Equine/Horse Iduronate 2 sulfatase/IDS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Iduronate 2 sulfatase/IDS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T28993-Ag | Human | Human Iduronate 2 sulfatase/IDS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T28993-Ag | Rat | Rat Iduronate 2 sulfatase/IDS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T28993-Ag | Mouse | Mouse Iduronate 2 sulfatase/IDS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T28993-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Iduronate 2 sulfatase/IDS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T28993-Ag | Cat/Feline | Cat/Feline Iduronate 2 sulfatase/IDS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T28993-Ag | Dog/Canine | Dog/Canine Iduronate 2 sulfatase/IDS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T28993-Ag | Bovines/Cattle | Bovines/Cattle Iduronate 2 sulfatase/IDS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T28993-Ag | Equine/Horse | Equine/Horse Iduronate 2 sulfatase/IDS recombinant protein | Mammalian cell | Detail |
