Explore HRH4/H4R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
| Target ID |
GM-T26500
|
| Target Name |
HRH4/H4R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
59340
|
| Gene ID |
100034111 (Equus caballus), 101100602 (Felis catus), 170704 (Rattus norvegicus), 225192 (Mus musculus)
490512 (Canis lupus familiaris), 59340 (Homo sapiens), 702044 (Macaca mulatta), 783354 (Bos taurus)
|
| Target Alternative Names |
AXOR35,BG26,G-protein coupled receptor 105,GPCR105,GPRv53,H4,H4R,HH4R,HRH4,Histamine H4 receptor,Hrh4,Pfi-013,SP9144
|
| Uniprot Accession |
Q91ZY1,Q91ZY2,Q9H3N8
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000006494, ENSMUSG00000037346, ENSCAFG00845013170, ENSG00000134489, ENSMMUG00000015065, ENSBTAG00000020467
|
| Target Classification |
GPCR
|
Pre-made viral vector of HRH4/H4R cDNA Clones/ORF Plasmid
HRH4/H4R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo59340 | Pre-made Human HRH4/H4/H4R siRNA oligo Duplex | 59340 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170704 | Pre-made Rat Hrh4 siRNA oligo Duplex | 170704 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo225192 | Pre-made Mouse Hrh4/H4/H4R siRNA oligo Duplex | 225192 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702044 | Pre-made Cynomolgus/Rhesus macaque HRH4 siRNA oligo Duplex | 702044 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100602 | Pre-made Cat/Feline HRH4 siRNA oligo Duplex | 101100602 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490512 | Pre-made Dog/Canine HRH4 siRNA oligo Duplex | 490512 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo783354 | Pre-made Bovines/Cattle HRH4 siRNA oligo Duplex | 783354 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034111 | Pre-made Equine/Horse HRH4 siRNA oligo Duplex | 100034111 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HRH4/H4R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T26500-Ab | Human | Anti-Human HRH4/H4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T26500-Ab | Rat | Anti-Rat HRH4/H4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T26500-Ab | Mouse | Anti-Mouse HRH4/H4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T26500-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HRH4/H4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T26500-Ab | Cat/Feline | Anti-Cat/Feline HRH4/H4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T26500-Ab | Dog/Canine | Anti-Dog/Canine HRH4/H4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T26500-Ab | Bovines/Cattle | Anti-Bovines/Cattle HRH4/H4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T26500-Ab | Equine/Horse | Anti-Equine/Horse HRH4/H4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HRH4/H4R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T26500-Ag | Human | Human HRH4/H4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T26500-Ag | Rat | Rat HRH4/H4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T26500-Ag | Mouse | Mouse HRH4/H4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T26500-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HRH4/H4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T26500-Ag | Cat/Feline | Cat/Feline HRH4/H4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T26500-Ag | Dog/Canine | Dog/Canine HRH4/H4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T26500-Ag | Bovines/Cattle | Bovines/Cattle HRH4/H4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T26500-Ag | Equine/Horse | Equine/Horse HRH4/H4R VLP (virus-like particle) | HEK293 | Products Developing |
