Explore DRD4/D4R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T24983
|
| Target Name |
DRD4/D4R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1815
|
| Gene ID |
100147552 (Equus caballus), 101906668 (Bos taurus), 111556768 (Felis catus), 119864199 (Canis lupus familiaris)
13491 (Mus musculus), 1815 (Homo sapiens), 25432 (Rattus norvegicus), 699697 (Macaca mulatta)
|
| Target Alternative Names |
D(2C) dopamine receptor,D(4) dopamine receptor,D4DR,D4R,D4RA,DRD4,Dopamine D4 receptor,Drd-4,Drd4
|
| Uniprot Accession |
P51436,P21917,P30729
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000010137, ENSBTAG00000051042, ENSCAFG00845017368, ENSMUSG00000025496, ENSG00000069696
|
| Target Classification |
GPCR
|
Pre-made viral vector of DRD4/D4R cDNA Clones/ORF Plasmid
DRD4/D4R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1815 | Pre-made Human DRD4/D4DR siRNA oligo Duplex | 1815 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25432 | Pre-made Rat Drd4/D4RA siRNA oligo Duplex | 25432 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13491 | Pre-made Mouse Drd4/D4R/Drd-4 siRNA oligo Duplex | 13491 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699697 | Pre-made Cynomolgus/Rhesus macaque DRD4 siRNA oligo Duplex | 699697 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111556768 | Pre-made Cat/Feline DRD4 siRNA oligo Duplex | 111556768 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119864199 | Pre-made Dog/Canine DRD4 siRNA oligo Duplex | 119864199 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101906668 | Pre-made Bovines/Cattle DRD4 siRNA oligo Duplex | 101906668 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147552 | Pre-made Equine/Horse DRD4 siRNA oligo Duplex | 100147552 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DRD4/D4R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T24983-Ab | Human | Anti-Human DRD4/D4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T24983-Ab | Rat | Anti-Rat DRD4/D4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T24983-Ab | Mouse | Anti-Mouse DRD4/D4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T24983-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DRD4/D4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T24983-Ab | Cat/Feline | Anti-Cat/Feline DRD4/D4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T24983-Ab | Dog/Canine | Anti-Dog/Canine DRD4/D4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T24983-Ab | Bovines/Cattle | Anti-Bovines/Cattle DRD4/D4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T24983-Ab | Equine/Horse | Anti-Equine/Horse DRD4/D4R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
DRD4/D4R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T24983-Ag | Human | Human DRD4/D4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T24983-Ag | Rat | Rat DRD4/D4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T24983-Ag | Mouse | Mouse DRD4/D4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T24983-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DRD4/D4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T24983-Ag | Cat/Feline | Cat/Feline DRD4/D4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T24983-Ag | Dog/Canine | Dog/Canine DRD4/D4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T24983-Ag | Bovines/Cattle | Bovines/Cattle DRD4/D4R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T24983-Ag | Equine/Horse | Equine/Horse DRD4/D4R VLP (virus-like particle) | HEK293 | Products Developing |
