Explore ASBT/SLC10A2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]
| Target ID |
GM-T24982
|
| Target Name |
ASBT/SLC10A2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6555
|
| Gene ID |
100051264 (Equus caballus), 101083393 (Felis catus), 20494 (Mus musculus), 29500 (Rattus norvegicus)
403448 (Canis lupus familiaris), 525823 (Bos taurus), 6555 (Homo sapiens), 702376 (Macaca mulatta)
|
| Target Alternative Names |
SLC10A2,Slc10a2,ASBT,IBAT,ISBT,9130221J18Rik,ISBAT,PBAM,NTCP2,PBAM1
|
| Uniprot Accession |
P70172,Q62633,Q12908
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Bile secretion
|
| Gene Ensembl |
ENSECAG00000006314, ENSMUSG00000023073, ENSCAFG00845027780, ENSBTAG00000005925, ENSG00000125255, ENSMMUG00000007664
|
| Target Classification |
|
Pre-made viral vector of ASBT/SLC10A2 cDNA Clones/ORF Plasmid
ASBT/SLC10A2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6555 | Pre-made Human SLC10A2/ASBT/IBAT siRNA oligo Duplex | 6555 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29500 | Pre-made Rat Slc10a2/ASBT/IBAT siRNA oligo Duplex | 29500 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20494 | Pre-made Mouse Slc10a2/ASBT/IBAT siRNA oligo Duplex | 20494 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702376 | Pre-made Cynomolgus/Rhesus macaque SLC10A2 siRNA oligo Duplex | 702376 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083393 | Pre-made Cat/Feline SLC10A2 siRNA oligo Duplex | 101083393 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403448 | Pre-made Dog/Canine SLC10A2 siRNA oligo Duplex | 403448 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525823 | Pre-made Bovines/Cattle SLC10A2 siRNA oligo Duplex | 525823 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051264 | Pre-made Equine/Horse SLC10A2 siRNA oligo Duplex | 100051264 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ASBT/SLC10A2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T24982-Ab | Human | Anti-Human ASBT/SLC10A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T24982-Ab | Rat | Anti-Rat ASBT/SLC10A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T24982-Ab | Mouse | Anti-Mouse ASBT/SLC10A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T24982-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ASBT/SLC10A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T24982-Ab | Cat/Feline | Anti-Cat/Feline ASBT/SLC10A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T24982-Ab | Dog/Canine | Anti-Dog/Canine ASBT/SLC10A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T24982-Ab | Bovines/Cattle | Anti-Bovines/Cattle ASBT/SLC10A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T24982-Ab | Equine/Horse | Anti-Equine/Horse ASBT/SLC10A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ASBT/SLC10A2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T24982-Ag | Human | Human ASBT/SLC10A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T24982-Ag | Rat | Rat ASBT/SLC10A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T24982-Ag | Mouse | Mouse ASBT/SLC10A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T24982-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ASBT/SLC10A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T24982-Ag | Cat/Feline | Cat/Feline ASBT/SLC10A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T24982-Ag | Dog/Canine | Dog/Canine ASBT/SLC10A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T24982-Ag | Bovines/Cattle | Bovines/Cattle ASBT/SLC10A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T24982-Ag | Equine/Horse | Equine/Horse ASBT/SLC10A2 VLP (virus-like particle) | HEK293 | Products Developing |
