MGMT Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore MGMT gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]

Target ID	GM-T24587
Target Name	MGMT
Gene Group ldentifer （Target Gene ID in Homo species)	4255
Gene ID	100049801 (Equus caballus), 101085076 (Felis catus), 17314 (Mus musculus), 25332 (Rattus norvegicus) 4255 (Homo sapiens), 442978 (Canis lupus familiaris), 616091 (Bos taurus), 698134 (Macaca mulatta)
Target Alternative Names	6-O-methylguanine-DNA methyltransferase (MGMT),AGT,Agat,MGMT,Methylated-DNA--protein-cysteine methyltransferase,Mgmt,O-6-methylguanine-DNA-alkyltransferase
Uniprot Accession	P26187,P24528,P16455,Q6TDU1,P29177
Protein Sub-location	Introcelluar Protein
Category	Therapeutics Target
Disease	cancer, Lung Cancer
Gene Ensembl	ENSECAG00000026858, ENSMUSG00000054612, ENSG00000170430, ENSCAFG00845028222, ENSBTAG00000050386, ENSMMUG00000011446

Pre-made viral vector of MGMT cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP004946	Human Mgmt Lentivirus plasmid	NM_002412	4255	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV000629	Human MGMT Lentivirus plasmid	NM_002412.4	4255	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV002195	Human MGMT Lentivirus plasmid	NM_002412.5	4255	Human	Lentivirus plasmid	ZsGreen	Null	CMV	Detail
vGMLP004946	Human Mgmt Lentivirus particle	NM_002412	4255	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV000629	Human MGMT Lentivirus particle	NM_002412.4	4255	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV002195	Human MGMT Lentivirus particle	NM_002412.5	4255	Human	Lentivirus particle	ZsGreen	Null	CMV	Detail
pGMLPm000491	Mouse Mgmt/Agat/AGT Lentivirus plasmid	NM_008598	17314	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLPm000491	Mouse Mgmt/Agat/AGT Lentivirus particle	NM_008598	17314	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

MGMT siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo4255	Pre-made Human MGMT siRNA oligo Duplex	4255	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo25332	Pre-made Rat Mgmt siRNA oligo Duplex	25332	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo17314	Pre-made Mouse Mgmt/AGT/Agat siRNA oligo Duplex	17314	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo698134	Pre-made Cynomolgus/Rhesus macaque MGMT siRNA oligo Duplex	698134	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101085076	Pre-made Cat/Feline MGMT siRNA oligo Duplex	101085076	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo442978	Pre-made Dog/Canine MGMT siRNA oligo Duplex	442978	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo616091	Pre-made Bovines/Cattle MGMT siRNA oligo Duplex	616091	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100049801	Pre-made Equine/Horse MGMT siRNA oligo Duplex	100049801	Equine/Horse	In-vitro grade; in-vivo grade	Detail

MGMT antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T24587-Ab	Human	Anti-Human MGMT monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-rg-T24587-Ab	Rat	Anti-Rat MGMT monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-mg-T24587-Ab	Mouse	Anti-Mouse MGMT monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cynog-T24587-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque MGMT monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-felg-T24587-Ab	Cat/Feline	Anti-Cat/Feline MGMT monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cang-T24587-Ab	Dog/Canine	Anti-Dog/Canine MGMT monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-bovg-T24587-Ab	Bovines/Cattle	Anti-Bovines/Cattle MGMT monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-equg-T24587-Ab	Equine/Horse	Anti-Equine/Horse MGMT monoclonal antibody	mab	Therapeutics Target antibody	Detail

MGMT recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T24587-Ag	Human	Human MGMT recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T24587-Ag	Rat	Rat MGMT recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T24587-Ag	Mouse	Mouse MGMT recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T24587-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque MGMT recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T24587-Ag	Cat/Feline	Cat/Feline MGMT recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T24587-Ag	Dog/Canine	Dog/Canine MGMT recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T24587-Ag	Bovines/Cattle	Bovines/Cattle MGMT recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T24587-Ag	Equine/Horse	Equine/Horse MGMT recombinant protein	Mammalian cell	Detail