Explore SERPING1/C1 Inactivator gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, May 2020]
| Target ID |
GM-T24211
|
| Target Name |
SERPING1/C1 Inactivator
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
710
|
| Gene ID |
100066476 (Equus caballus), 101087683 (Felis catus), 12258 (Mus musculus), 281035 (Bos taurus)
295703 (Rattus norvegicus), 475966 (Canis lupus familiaris), 703928 (Macaca mulatta), 710 (Homo sapiens)
|
| Target Alternative Names |
C1 Inactivator,C1 Inh,C1 esterase inhibitor,C1-IA,C1-inhibiting factor,C1IN,C1INH,C1INH.,C1Inh,C1NH,C1nh,HAE1,HAE2,Plasma protease C1 inhibitor,SERPING1,Serpin G1,Serping1
|
| Uniprot Accession |
P97290,P50448,Q6P734,P05155
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Complement and coagulation cascades, Pertussis
|
| Gene Ensembl |
ENSECAG00000010963, ENSMUSG00000023224, ENSBTAG00000016267, ENSCAFG00845020645, ENSMMUG00000012618, ENSG00000149131
|
Pre-made viral vector of SERPING1/C1 Inactivator cDNA Clones/ORF Plasmid
SERPING1/C1 Inactivator siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo710 | Pre-made Human SERPING1/C1IN/C1NH siRNA oligo Duplex | 710 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo295703 | Pre-made Rat Serping1/C1-IA siRNA oligo Duplex | 295703 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12258 | Pre-made Mouse Serping1/C1nh/C1Inh siRNA oligo Duplex | 12258 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703928 | Pre-made Cynomolgus/Rhesus macaque SERPING1 siRNA oligo Duplex | 703928 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087683 | Pre-made Cat/Feline SERPING1 siRNA oligo Duplex | 101087683 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475966 | Pre-made Dog/Canine SERPING1 siRNA oligo Duplex | 475966 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281035 | Pre-made Bovines/Cattle SERPING1/C1NH siRNA oligo Duplex | 281035 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066476 | Pre-made Equine/Horse SERPING1 siRNA oligo Duplex | 100066476 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SERPING1/C1 Inactivator antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T24211-Ab | Human | Anti-Human SERPING1/C1 Inactivator monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T24211-Ab | Rat | Anti-Rat SERPING1/C1 Inactivator monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T24211-Ab | Mouse | Anti-Mouse SERPING1/C1 Inactivator monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T24211-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SERPING1/C1 Inactivator monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T24211-Ab | Cat/Feline | Anti-Cat/Feline SERPING1/C1 Inactivator monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T24211-Ab | Dog/Canine | Anti-Dog/Canine SERPING1/C1 Inactivator monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T24211-Ab | Bovines/Cattle | Anti-Bovines/Cattle SERPING1/C1 Inactivator monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T24211-Ab | Equine/Horse | Anti-Equine/Horse SERPING1/C1 Inactivator monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SERPING1/C1 Inactivator recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T24211-Ag | Human | Human SERPING1/C1 Inactivator recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T24211-Ag | Rat | Rat SERPING1/C1 Inactivator recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T24211-Ag | Mouse | Mouse SERPING1/C1 Inactivator recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T24211-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SERPING1/C1 Inactivator recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T24211-Ag | Cat/Feline | Cat/Feline SERPING1/C1 Inactivator recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T24211-Ag | Dog/Canine | Dog/Canine SERPING1/C1 Inactivator recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T24211-Ag | Bovines/Cattle | Bovines/Cattle SERPING1/C1 Inactivator recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T24211-Ag | Equine/Horse | Equine/Horse SERPING1/C1 Inactivator recombinant protein | Mammalian cell | Detail |
